DPhPC;1,2-diphytanoyl-sn-glycero-3-phosphocholine

DPhPC;1,2-diphytanoyl-sn-glycero-3-phosphocholine

Chemical Name

[(2R)-2,3-bis(3,7,11,15-tetramethylhexadecanoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate

DPhPC;1,2-diphytanoyl-sn-glycero-3-phosphocholineLNP
Structure: DPhPC;1,2-diphytanoyl-sn-glycero-3-phosphocholine structure, CAS 207131-40-6, MW 846.25
Product No
CH51063
CAS
207131-40-6
MF
C48H96NO8P
MW
846.25
Specification
Catalog No.CH51063
CAS No.207131-40-6
Molecular FormulaC48H96NO8P
Molecular Weight846.25

CHEMOS Support for This Category

CHEMOS supports custom synthesis and process development for LNP lipid components, with work planned according to target structure, requested scale, and analytical requirements. Ionizable lipid route development : route scouting, impurity review, stereochemistry control, and purification planning. Helper lipid and PEG-lipid preparation : support for phospholipids, sterol-related components, PEG-lipids, and related analogs. Analytical support : HPLC, NMR, MS, Karl Fischer water content, elemental analysis, and residual-solvent testing can be discussed by project. Scale-up support : transfer from laboratory preparation to larger pilot or production batches after route and quality review. Project documentation : batch-specific COA and technical information are provided according to the confirmed specification.

Overview

DPhPC;1,2-diphytanoyl-sn-glycero-3-phosphocholine (also known as [(2R)-2,3-bis(3,7,11,15-tetramethylhexadecanoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate) (CAS 207131-40-6, MF C48H96NO8P, MW 846.25) is a helper-lipid phospholipid component of relevance to liposome and LNP research. Programs working with this lipid focus on chain-length specificity, oxidation control for unsaturated tails, and analytical separation of related species. Project scale-up and custom synthesis are coordinated by the CHEMOS R&D team across laboratory and production sites.

Applications

  • DPhPC;1,2-diphytanoyl-sn-glycero-3-phosphocholine (CAS 207131-40-6) preparation, route refinement, and analytical-control planning
  • Custom synthesis of acyl-chain or head-group variants
  • Reference material in liposome composition optimisation studies
  • Bilayer-property studies in nucleic-acid delivery system development

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