Fmoc-8-amino-3,6-dioxaoctanoic acid
Fmoc-8-amino-3,6-dioxaoctanoic acid

Product summary
Quick view
- Product family
- ADC Linkers & Conjugation Reagents
- Chemical Name
- Fmoc-8-amino-3,6-dioxaoctanoic acid
- MF
- C21H23NO6
- MW
- 385.41
Fmoc-8-amino-3,6-dioxaoctanoic acid is the product name used for CH53001.
CAS 166108-71-0, molecular formula C21H23NO6, molecular weight about 385.4, and PubChem CID 2756092 match this compound record.
The IUPAC name is 2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]acetic acid.
Identity and specifications
| Catalog No. | CH53001 |
| CAS No. | 166108-71-0 |
| Chemical Name | Fmoc-8-amino-3,6-dioxaoctanoic acid |
| IUPAC Name | 2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]acetic acid |
| Molecular Formula | C21H23NO6 |
| Molecular Weight | 385.41 |
| PubChem CID | 2756092 |
Related technical resources
ADC Linker-Payload Chemistry
Cleavable linkers, stable linkers, hydrophilic spacers, site-selective handles, and payload-linker intermediate chemistry.
Cleavable vs Non-cleavable ADC Linkers
Compare ADC linker strategies by released species, trigger, circulation stability, intracellular processing, payload properties, conjugation format, and analytical evidence.
Public references
- 2-(2-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)ethoxy)ethoxy)acetic acid | PubChem CID 2756092
- Development of Solid-Phase Site-Specific Conjugation and Its Application toward Generation of Dual Labeled Antibody and Fab Drug Conjugates
Bioconjugate Chemistry, 2016
Product-family technical context
- Effect of Linker-Drug Properties and Conjugation Site on the Physical Stability of ADCs
Journal of Pharmaceutical Sciences, 2020
Product-family technical context
- Antibody-Maytansinoid Conjugates Are Activated in Targeted Cancer Cells by Lysosomal Degradation and Linker-Dependent Intracellular Processing
Cancer Research, 2006
Product-family technical context
- The Effect of Different Linkers on Target Cell Catabolism and Pharmacokinetics/Pharmacodynamics of Trastuzumab Maytansinoid Conjugates
Molecular Cancer Therapeutics, 2012
Product-family technical context
Frequently Asked Questions
What is Fmoc-8-amino-3,6-dioxaoctanoic acid?
Fmoc-8-amino-3,6-dioxaoctanoic acid is the product name used for CH53001.
Similar Products
Need Help with Material Selection?
CHEMOS can review product fit, target structure, route questions, analytical expectations, and project-specific supply needs.



