CHEMOS
Boc-C16-COOH

Boc-C16-COOH

Chemical Name

18-[(2-methylpropan-2-yl)oxy]-18-oxooctadecanoic acid

Boc-C16-COOH•ADC linker
Structure: Boc-C16-COOH structure, CAS 843666-40-0, MW 370.57
Product No
CH53003
CAS
843666-40-0
MF
C22H42O4
MW
370.57
Specification
Catalog No.CH53003
CAS No.843666-40-0
Molecular FormulaC22H42O4
Molecular Weight370.57

CHEMOS Support for This Category

CHEMOS supports ADC linker and bioconjugation building-block projects from route design through custom synthesis and process optimization. Custom linker synthesis : peptide, PEG, self-immolative, cleavable, and non-cleavable linker structures. Functional-handle installation : NHS ester, maleimide, azide, alkyne, and other conjugation-ready groups. Multi-step route development : protecting-group strategy, coupling optimization, purification review, and impurity-profile control. Analytical support : HPLC, NMR, MS, and chiral methods where applicable. Scale-up planning : laboratory-to-production transfer can be evaluated after route feasibility and specification review.

Overview

Boc-C16-COOH (also known as 18-[(2-methylpropan-2-yl)oxy]-18-oxooctadecanoic acid) (CAS 843666-40-0, MF C22H42O4, MW 370.57) belongs to the ADC linker / bioconjugation handle class. Practical chemistry questions involve the conjugation chemistry, peptide-cleavable element design (where applicable), and analytical control of related impurities. Project scale-up and custom synthesis are coordinated by the CHEMOS R&D team across laboratory and production sites.

Applications

  • Boc-C16-COOH (843666-40-0) supply and analog preparation for research programs
  • Bioconjugation handle for site-specific cysteine / lysine attachment
  • Cleavable peptide-linker design and intracellular-release studies
  • Click-chemistry coupling (DBCO / azide) for bioconjugation programs

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