CHEMOS
Boc-Hyp-OH

Boc-Hyp-OH

Chemical Name

(2S,4R)-4-hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid

Boc-Hyp-OH•ADC linker
Structure: Boc-Hyp-OH structure, CAS 13726-69-7, MW 231.25
Product No
CH53004
CAS
13726-69-7
MF
C10H17NO5
MW
231.25
Specification
Catalog No.CH53004
CAS No.13726-69-7
Molecular FormulaC10H17NO5
Molecular Weight231.25

CHEMOS Support for This Category

CHEMOS supports ADC linker and bioconjugation building-block projects from route design through custom synthesis and process optimization. Custom linker synthesis : peptide, PEG, self-immolative, cleavable, and non-cleavable linker structures. Functional-handle installation : NHS ester, maleimide, azide, alkyne, and other conjugation-ready groups. Multi-step route development : protecting-group strategy, coupling optimization, purification review, and impurity-profile control. Analytical support : HPLC, NMR, MS, and chiral methods where applicable. Scale-up planning : laboratory-to-production transfer can be evaluated after route feasibility and specification review.

Overview

Boc-Hyp-OH (also known as (2S,4R)-4-hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid) (CAS 13726-69-7, MF C10H17NO5, MW 231.25) is an antibody-drug conjugate (ADC) linker or bioconjugation building block. Chemistry topics around such compounds typically cover the reactive handle (maleimide / NHS / DBCO / azide), linker stability in plasma, and release behaviour intracellularly. Bench-scale to larger-scale production is supported through CHEMOS organic chemistry workflows and dedicated process-development resources.

Applications

  • Boc-Hyp-OH (13726-69-7) as a starting point for downstream chemistry programs
  • Click-chemistry coupling (DBCO / azide) for bioconjugation programs
  • Process-development support for scalable linker preparation
  • Bioconjugation handle for site-specific cysteine / lysine attachment

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