H-Glu-OtBu
(4S)-4-amino-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoic acid

Product summary
Quick view
- Product family
- ADC Linkers & Conjugation Reagents
- Chemical Name
- (4S)-4-amino-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoic acid
- MF
- C9H17NO4
- MW
- 203.24
H-Glu-OtBu corresponds to a tert-butyl glutamate record.
CAS 45120-30-7, molecular formula C9H17NO4, molecular weight 203.24, and PubChem CID 117505 match this CH53009 record.
The PubChem IUPAC name identifies the compound with (4S) stereochemistry.
Identity and specifications
| Catalog No. | CH53009 |
| CAS No. | 45120-30-7 |
| Chemical Name | (4S)-4-amino-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoic acid |
| Molecular Formula | C9H17NO4 |
| Molecular Weight | 203.24 |
| PubChem CID | 117505 |
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Public references
- 1-(1,1-Dimethylethyl) hydrogen L-glutamate | PubChem CID 117505
- Development of Solid-Phase Site-Specific Conjugation and Its Application toward Generation of Dual Labeled Antibody and Fab Drug Conjugates
Bioconjugate Chemistry, 2016
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- Effect of Linker-Drug Properties and Conjugation Site on the Physical Stability of ADCs
Journal of Pharmaceutical Sciences, 2020
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- Antibody-Maytansinoid Conjugates Are Activated in Targeted Cancer Cells by Lysosomal Degradation and Linker-Dependent Intracellular Processing
Cancer Research, 2006
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- The Effect of Different Linkers on Target Cell Catabolism and Pharmacokinetics/Pharmacodynamics of Trastuzumab Maytansinoid Conjugates
Molecular Cancer Therapeutics, 2012
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Frequently Asked Questions
What is H-Glu-OtBu?
H-Glu-OtBu corresponds to a tert-butyl glutamate record.
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