CHEMOS
Boc-β-Ala-OH

Boc-β-Ala-OH

Chemical Name

3-[(tert-butoxycarbonyl)amino]propanoic acid

Boc-β-Ala-OH•PROTAC
Structure: Boc-β-Ala-OH structure, CAS 3303-84-2, MW 189.21
Product No
CH56017
CAS
3303-84-2
MF
C8H15NO4
MW
189.21
Specification
Catalog No.CH56017
CAS No.3303-84-2
Molecular FormulaC8H15NO4
Molecular Weight189.21

CHEMOS Support for This Category

CHEMOS supports PROTAC building-block projects covering linkers, E3 ligase recruiter derivatives, and customized degrader intermediates. Linker building blocks : PEG acids, PEG azides, alkyl spacers, branched linkers, and rigid linkers. E3 recruiter derivatives : IMiD-related, VHL-related, and other recruiter building blocks for medicinal chemistry programs. Custom synthesis : linker design, functional-group installation, and intermediate preparation. Route and purification review : multi-step synthesis planning with attention to polarity, solubility, and impurity control. Scale-up evaluation : larger-batch preparation can be assessed after route feasibility review.

Overview

Boc-β-Ala-OH (also known as 3-[(tert-butoxycarbonyl)amino]propanoic acid) (CAS 3303-84-2, MF C8H15NO4, MW 189.21) is used as a PROTAC research building block in degrader chemistry. Typical chemistry questions involve route design for the bifunctional architecture, linker selection, and analytical control of residual reagents. CHEMOS process-development team and large production base can support route refinement, scale-up and custom synthesis on request.

Applications

  • Boc-β-Ala-OH (CAS 3303-84-2) preparation, route refinement, and analytical-control planning
  • Reference material in targeted protein degradation chemistry programs
  • PROTAC building block — linker / E3-ligand / degrader handle
  • Bifunctional degrader synthesis with orthogonal protecting groups

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