CHEMOS
1H-1,4-Benzodiazepine-7-carbonitrile, 2,3,4,5-tetrahydro-1-[(1-methyl-1H-imidazol-5-yl)methyl]-3-(phenylmethyl)-4-(2-thienylsulfonyl)-, (3R)-

1H-1,4-Benzodiazepine-7-carbonitrile, 2,3,4,5-tetrahydro-1-[(1-methyl-1H-imidazol-5-yl)methyl]-3-(phenylmethyl)-4-(2-thienylsulfonyl)-, (3R)-

1H-1,4-Benzodiazepine-7-carbonitrile, 2,3,4,5-tetrahydro-1-[(1-methyl-1H-imidazol-5-yl)methyl]-3-(phenylmethyl)-4-(2-thienylsulfonyl)-, (3R)-•Molecular Glues
Structure: 1H-1,4-Benzodiazepine-7-carbonitrile, 2,3,4,5-tetrahydro-1-[(1-methyl-1H-imidazol-5-yl)methyl]-3-(phenylmethyl)-4-(2-thienylsulfonyl)-, (3R)- structure, CAS 675125-62-9, MW 503.64
Product No
CH57014
CAS
675125-62-9
MW
503.64
Specification
Catalog No.CH57014
CAS No.675125-62-9
Molecular Weight503.64

CHEMOS Support for This Category

CHEMOS supports molecular glue and small-molecule degrader building-block chemistry, including analog preparation and route optimization. Scaffold preparation : IMiD-related analogs, sulfonamide motifs, and other functionalized small-molecule scaffolds. Custom analog synthesis : substituent variation, linker-ready handles, and SAR-oriented intermediate preparation. Chiral and stereochemical review : chiral separation or asymmetric synthesis can be evaluated where relevant. Analytical support : HPLC, NMR, MS, and purity-method development according to project needs. Process development : route refinement and scale-up planning after technical review.

Overview

1H-1,4-Benzodiazepine-7-carbonitrile, 2,3,4,5-tetrahydro-1-[(1-methyl-1H-imidazol-5-yl)methyl]-3-(phenylmethyl)-4-(2-thienylsulfonyl)-, (3R)- (CAS 675125-62-9, MW 503.64) is part of the small-molecule research-tool class for targeted protein degradation programs (molecular glue or related modality). Programs working with this compound typically examine stereo-purity, analog series, and the behaviour of the warhead under storage. Bench-scale to larger-scale production is supported through CHEMOS organic chemistry workflows and dedicated process-development resources.

Applications

  • 1H-1,4-Benzodiazepine-7-carbonitrile, 2,3,4,5-tetrahydro-1-[(1-methyl-1H-imidazol-5-yl)methyl]-3-(phenylmethyl)-4-(2-thienylsulfonyl)-, (3R)- (675125-62-9) supply and analog preparation for research programs
  • Molecular glue research scaffold for targeted protein degradation
  • Custom synthesis of analog series for SAR exploration
  • Reference research scaffold in degrader chemistry programs

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