2'-Deoxyguanosine Monohydrate
2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one;hydrate
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Chemical Name
- 2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one;hydrate
- MF
- C10H15N5O5
- MW
- 285.26
- Purity
- 99.4% (HPLC)
2'-Deoxyguanosine monohydrate is the hydrated dGuo form of the purine DNA nucleoside, with guanine linked to 2-deoxy-β-D-ribose. CH64003 is listed under CAS 312693-72-4, molecular formula C10H15N5O5, molecular weight 285.26, and PubChem CID 135445705.
Keep this monohydrate record separate from anhydrous 2'-deoxyguanosine, which is cataloged separately as CH64008. In nucleoside research, deoxyguanosine is used as a deoxyguanosine-kinase substrate and as the canonical dG reference for purine DNA nucleoside chemistry.
Synonyms
2'-Deoxyguanosine monohydrate; dGuo monohydrate; 2'-deoxyriboguanosine hydrate
Identity and specifications
| Catalog No. | CH64003 |
| CAS No. | 312693-72-4 |
| Molecular Formula | C10H15N5O5 (monohydrate) |
| Molecular Weight | 285.26 (monohydrate) |
| PubChem CID | 135445705 |
| InChIKey | LZSCQUCOIRGCEJ-FPKZOZHISA-N |
| Purity | 99.4% (HPLC) |
Storage conditions
-20 C
Technical attributes
- Nucleobase
- Guanine
- Sugar
- 2'-Deoxyribose
- Nucleoside class
- Purine 2'-deoxyribonucleoside
- Material form
- Monohydrate
- Packaging
- Custom packaging on request
- Water content
- Karl Fischer 6.1% w/w
- Physical form
- Solid
- Stability
- >=4 years
Application context
- Salvage-pathway phosphorylation research: literature reports deoxyguanosine as a substrate of deoxyguanosine kinase (dGK).
- Purine DNA nucleoside reference: CH64003 provides the monohydrate dG identity for nucleoside and oligonucleotide chemistry comparisons.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 135445705
PubChem · CID 135445705
Frequently Asked Questions
Is CH64003 the monohydrate or anhydrous form?
It is the monohydrate (CAS 312693-72-4, C10H15N5O5, MW 285.26). The anhydrous 2'-deoxyguanosine (CAS 961-07-9) is listed as a separate CHEMOS product.
How is deoxyguanosine used in kinase research?
It is phosphorylated by deoxyguanosine kinase (dGK) in the nucleoside salvage pathway, so it serves as a defined purine deoxynucleoside substrate in phosphorylation studies.
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