2'-Deoxyadenosine (anhydrous)
(2R,3S,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Chemical Name
- (2R,3S,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
- MF
- C10H13N5O3
- MW
- 251.24
- Purity
- >98.0% (HPLC, titration)
2'-Deoxyadenosine is the anhydrous dAdo form of the purine DNA nucleoside, with adenine linked to 2-deoxy-β-D-ribose. CH64007 is identified by CAS 958-09-8, molecular formula C10H13N5O3, molecular weight 251.24, and PubChem CID 13730.
Keep this record separate from 2'-deoxyadenosine monohydrate, which is listed separately as CH64001. In research literature, 2'-deoxyadenosine appears as a deoxynucleoside-kinase substrate and as the natural dA reference in polymerase and nucleoside-chemistry studies.
Synonyms
2'-Deoxyadenosine; deoxyadenosine; dAdo; dA (nucleoside)
Identity and specifications
| Catalog No. | CH64007 |
| CAS No. | 958-09-8 |
| Molecular Formula | C10H13N5O3 (anhydrous) |
| Molecular Weight | 251.24 (anhydrous) |
| PubChem CID | 13730 |
| InChIKey | OLXZPDWKRNYJJZ-RRKCRQDMSA-N |
| Purity | >98.0% (HPLC, titration) |
Storage conditions
0-10 C
Technical attributes
- Nucleobase
- Adenine
- Sugar
- 2'-Deoxyribose
- Nucleoside class
- Purine 2'-deoxyribonucleoside
- Material form
- Anhydrous
- Packaging
- Custom packaging on request
- Physical form
- Solid; white to almost white powder to crystal
Application context
- Kinase phosphorylation research: literature reports 2'-deoxyadenosine as a substrate for deoxycytidine kinase and adenosine kinase.
- Polymerase building-block studies: modified dA building blocks are compared against the natural deoxyribonucleoside scaffold during polymerase-incorporation research.
- Purine DNA nucleoside reference: CH64007 provides the anhydrous dAdo identity for nucleoside and oligonucleotide chemistry comparisons.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 13730
PubChem · CID 13730
Frequently Asked Questions
Is CH64007 the anhydrous or monohydrate form?
It is the anhydrous form (CAS 958-09-8, C10H13N5O3, MW 251.24). The monohydrate 2'-deoxyadenosine (CAS 16373-93-6) is listed as a separate CHEMOS product.
How is 2'-deoxyadenosine used as a kinase substrate?
It is phosphorylated by deoxycytidine kinase and adenosine kinase, so it is used as a defined purine deoxynucleoside substrate in phosphorylation research.
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