2'-Deoxyguanosine (anhydrous)
2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Chemical Name
- 2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
- MF
- C10H13N5O4
- MW
- 267.24
- Purity
- >99.0% (HPLC)
2'-Deoxyguanosine is the anhydrous dGuo form of the purine DNA nucleoside, with guanine linked to 2-deoxy-β-D-ribose. CH64008 is identified by CAS 961-07-9, molecular formula C10H13N5O4, molecular weight 267.24, and PubChem CID 135398592.
Keep this record separate from CH64003, the monohydrate 2'-deoxyguanosine entry. The supported use context is research-facing: dGuo appears as a deoxyguanosine-kinase substrate in salvage-phosphorylation studies and as a canonical purine 2'-deoxyribonucleoside reference in nucleoside chemistry.
Synonyms
2'-Deoxyguanosine; deoxyguanosine; dGuo; dG (nucleoside)
Identity and specifications
| Catalog No. | CH64008 |
| CAS No. | 961-07-9 |
| Molecular Formula | C10H13N5O4 (anhydrous) |
| Molecular Weight | 267.24 (anhydrous) |
| PubChem CID | 135398592 |
| InChIKey | YKBGVTZYEHREMT-KVQBGUIXSA-N |
| Purity | >99.0% (HPLC) |
Storage conditions
Room temperature; cool and dark place below 15 C; inert gas
Technical attributes
- Nucleobase
- Guanine
- Sugar
- 2'-Deoxyribose
- Nucleoside class
- Purine 2'-deoxyribonucleoside
- Material form
- Anhydrous
- Packaging
- 1 g glass bottle with plastic insert; Custom packaging on request
- Water content
- <=10.0%
- Physical form
- Solid; white to almost white powder to crystal
Application context
- Deoxyguanosine kinase substrate: dGuo is used as the defined purine deoxynucleoside substrate in deoxyguanosine-kinase salvage-phosphorylation research.
- Purine DNA nucleoside reference: CH64008 provides the anhydrous dGuo identity for nucleoside and oligonucleotide chemistry comparisons.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 135398592
PubChem · CID 135398592
Frequently Asked Questions
Is CH64008 the anhydrous or monohydrate form?
It is the anhydrous form (CAS 961-07-9, C10H13N5O4, MW 267.24). The monohydrate 2'-deoxyguanosine (CAS 312693-72-4) is listed as a separate CHEMOS product.
How is deoxyguanosine used in kinase research?
It is phosphorylated by deoxyguanosine kinase (dGK) in the nucleoside salvage pathway, so it serves as a defined purine deoxynucleoside substrate in phosphorylation studies.
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