Cytidine
4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Chemical Name
- 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
- MF
- C9H13N3O5
- MW
- 243.22
- Purity
- >98.0% (HPLC, titration)
Cytidine is the canonical pyrimidine RNA nucleoside, with cytosine linked to β-D-ribose. CH64010 is identified by CAS 65-46-3, molecular formula C9H13N3O5, molecular weight 243.22, and PubChem CID 6175. It is the ribose counterpart of 2'-deoxycytidine, which is cataloged separately as CH64002.
The supported research context is pyrimidine salvage and RNA nucleoside chemistry: cytidine is a uridine-cytidine kinase substrate and an unmodified pyrimidine ribonucleoside reference.
Synonyms
Cytidine; cytosine riboside; Cyd
Identity and specifications
| Catalog No. | CH64010 |
| CAS No. | 65-46-3 |
| Molecular Formula | C9H13N3O5 |
| Molecular Weight | 243.22 |
| PubChem CID | 6175 |
| InChIKey | UHDGCWIWMRVCDJ-XVFCMESISA-N |
| Purity | >98.0% (HPLC, titration) |
Storage conditions
Room temperature; cool and dark place below 15 C; inert gas
Technical attributes
- Nucleobase
- Cytosine
- Sugar
- D-Ribose
- Nucleoside class
- Pyrimidine ribonucleoside
- Packaging
- 1 g glass bottle with plastic insert; Custom packaging on request
- Physical form
- Solid; white to almost white powder to crystal
- Stability
- >=4 years
Application context
- Uridine-cytidine kinase substrate: cytidine is phosphorylated by UCK in pyrimidine-nucleotide salvage research.
- Pyrimidine RNA nucleoside reference: CH64010 provides the unmodified cytidine identity for RNA and nucleoside chemistry comparisons.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 6175
PubChem · CID 6175
Frequently Asked Questions
Is CH64010 the RNA or DNA nucleoside?
It is cytidine, the RNA (ribo) nucleoside. The DNA counterpart, 2'-deoxycytidine, is listed separately by CHEMOS.
Why is cytidine used in salvage-pathway research?
Cytidine is a substrate of uridine-cytidine kinase, the rate-limiting enzyme of pyrimidine-nucleotide salvage, so it serves as a reference substrate in salvage studies.
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