Guanosine
2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Chemical Name
- 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
- MF
- C10H13N5O5
- MW
- 283.24
- Purity
- >98.0% (HPLC, titration)
Guanosine is the canonical purine RNA nucleoside, with guanine linked to β-D-ribose. CH64011 is identified by CAS 118-00-3, molecular formula C10H13N5O5, molecular weight 283.24, and PubChem CID 135398635. The corresponding 2'-deoxyguanosine records are cataloged separately.
The supported research context is PNP enzymology and RNA nucleoside chemistry: guanosine is a purine nucleoside phosphorylase substrate and an unmodified purine ribonucleoside reference.
Synonyms
Guanosine; guanine riboside; Guo
Identity and specifications
| Catalog No. | CH64011 |
| CAS No. | 118-00-3 |
| Molecular Formula | C10H13N5O5 |
| Molecular Weight | 283.24 |
| PubChem CID | 135398635 |
| InChIKey | NYHBQMYGNKIUIF-UUOKFMHZSA-N |
| Purity | >98.0% (HPLC, titration) |
Storage conditions
Room temperature; cool and dark place below 15 C
Technical attributes
- Nucleobase
- Guanine
- Sugar
- D-Ribose
- Nucleoside class
- Purine ribonucleoside
- Packaging
- 5 g; 25 g; 100 g; Custom packaging on request
- Physical form
- Solid; white to almost white powder to crystal
Application context
- Purine nucleoside phosphorylase substrate: guanosine is used as a defined substrate in PNP enzymology research.
- Purine RNA nucleoside reference: CH64011 provides the unmodified guanosine identity for RNA and nucleoside chemistry comparisons.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 135398635
PubChem · CID 135398635
Frequently Asked Questions
Is CH64011 the RNA or DNA nucleoside?
It is guanosine, the RNA (ribo) nucleoside. The DNA counterpart, 2'-deoxyguanosine, is listed separately by CHEMOS.
How is guanosine used in enzyme research?
Guanosine is a substrate of purine nucleoside phosphorylase (PNP), which phosphorolyzes purine ribonucleosides, so it is used as a reference substrate in PNP enzymology.
Similar Products
Need Help with Material Selection?
CHEMOS can review product fit, target structure, route questions, analytical expectations, and project-specific supply needs.