Uridine
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Chemical Name
- 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
- MF
- C9H12N2O6
- MW
- 244.20
- Purity
- 99.3% (HPLC)
Uridine is the canonical pyrimidine RNA nucleoside, with uracil linked to β-D-ribose. CH64012 is identified by CAS 58-96-8, molecular formula C9H12N2O6, molecular weight 244.20, and PubChem CID 6029. It is the ribose counterpart of 2'-deoxyuridine, which is cataloged separately as CH64005.
The supported research context is pyrimidine nucleoside phosphorylase enzymology and RNA nucleoside chemistry: uridine is a phosphorylase substrate and an unmodified pyrimidine ribonucleoside reference.
Synonyms
Uridine; uracil riboside; Urd
Identity and specifications
| Catalog No. | CH64012 |
| CAS No. | 58-96-8 |
| Molecular Formula | C9H12N2O6 |
| Molecular Weight | 244.20 |
| PubChem CID | 6029 |
| InChIKey | DRTQHJPVMGBUCF-XVFCMESISA-N |
| Purity | 99.3% (HPLC) |
Storage conditions
Room temperature; cool and dark place below 15 C
Technical attributes
- Nucleobase
- Uracil
- Sugar
- D-Ribose
- Nucleoside class
- Pyrimidine ribonucleoside
- Packaging
- 5 g; 25 g; 100 g; Custom packaging on request
- Water content
- Karl Fischer result 0.17%
- Physical form
- Solid; white powder to crystal
- Stability
- >=4 years
Application context
- Nucleoside phosphorylase substrate: uridine is phosphorolyzed by pyrimidine nucleoside phosphorylases in enzymology research.
- Pyrimidine RNA nucleoside reference: CH64012 provides the unmodified uridine identity for RNA and nucleoside chemistry comparisons.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 6029
PubChem · CID 6029
Frequently Asked Questions
Is CH64012 the RNA or DNA nucleoside?
It is uridine, the RNA (ribo) nucleoside. The DNA counterpart, 2'-deoxyuridine, is listed separately by CHEMOS.
How is uridine used in enzyme research?
Uridine is phosphorolyzed by pyrimidine (uridine) nucleoside phosphorylases, so it is used as a reference substrate in phosphorylase enzymology.
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