Inosine
9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Chemical Name
- 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
- MF
- C10H12N4O5
- MW
- 268.23
- Purity
- 100.0% (HPLC)
Inosine is the purine RNA nucleoside with hypoxanthine linked to β-D-ribose. CH64013 is identified by CAS 58-63-9, molecular formula C10H12N4O5, molecular weight 268.23, and PubChem CID 135398641. It is the ribose counterpart of 2'-deoxyinosine, which is cataloged separately as CH64006.
The supported research context is PNP enzymology and RNA nucleoside chemistry: inosine is a purine nucleoside phosphorylase substrate and a hypoxanthine ribonucleoside reference.
Synonyms
Inosine; hypoxanthine riboside; Ino
Identity and specifications
| Catalog No. | CH64013 |
| CAS No. | 58-63-9 |
| Molecular Formula | C10H12N4O5 |
| Molecular Weight | 268.23 |
| PubChem CID | 135398641 |
| InChIKey | UGQMRVRMYYASKQ-KQYNXXCUSA-N |
| Purity | 100.0% (HPLC) |
Storage conditions
-20 C
Technical attributes
- Nucleobase
- Hypoxanthine
- Sugar
- D-Ribose
- Nucleoside class
- Purine ribonucleoside
- Packaging
- Custom packaging on request
- Physical form
- Solid
- Stability
- >=4 years
Application context
- Purine nucleoside phosphorylase substrate: inosine is used as a defined substrate in PNP structural and enzymology research.
- Purine RNA nucleoside reference: CH64013 provides the hypoxanthine ribonucleoside identity for RNA and nucleoside chemistry comparisons.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 135398641
PubChem · CID 135398641
Frequently Asked Questions
Is CH64013 the RNA or DNA nucleoside?
It is inosine, the RNA (ribo) nucleoside. The DNA counterpart, 2'-deoxyinosine, is listed separately by CHEMOS.
How is inosine used in enzyme research?
Inosine is a substrate of purine nucleoside phosphorylase (PNP), which phosphorolyzes it to hypoxanthine and ribose-1-phosphate, so it serves as a reference substrate in PNP enzymology.
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