L-Guanosine
Oligonucleotide Synthesis, RNA Raw Materials & Modification
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- MF
- C10H13N5O5
- MW
- 283.24
- Purity
- 98%
L-Guanosine is the L-enantiomer, or mirror-image form, of natural D-guanosine. CH64037 is identified by CAS 26578-09-6, molecular formula C10H13N5O5, molecular weight 283.24, and PubChem CID 135484501.
The cited Spiegelmer literature discusses L-configured oligonucleotides as mirror-image systems with high biostability in nuclease-related studies. CH64037 provides the L-guanosine identity for related L-RNA, Spiegelmer aptamer, and nucleoside stereochemistry research.
Synonyms
L-Guanosine; β-L-guanosine
Identity and specifications
| Catalog No. | CH64037 |
| CAS No. | 26578-09-6 |
| Molecular Formula | C10H13N5O5 |
| Molecular Weight | 283.24 |
| PubChem CID | 135484501 |
| InChIKey | NYHBQMYGNKIUIF-GIMIYPNGSA-N |
| Purity | 98% |
Storage conditions
4 C for supplied solid; -80 C or -20 C in solvent
Technical attributes
- Nucleobase
- Guanine
- Sugar
- L-Ribose
- Nucleoside class
- Purine L-ribonucleoside
- Research role
- Mirror-image nucleic-acid building-block reference
- Packaging
- 100 mg; 250 mg; 1 g; Custom packaging on request
- Physical form
- Solid; white to off-white
- Stability
- 6 months in solvent at -80 C; 1 month in solvent at -20 C
Application context
- Mirror-image / Spiegelmer research: CH64037 is relevant to studies of mirror-image (L-RNA) oligonucleotides and Spiegelmer aptamers.
- Enantiomeric nucleoside studies: L-guanosine provides the guanosine mirror-image identity for stereochemistry and biostability comparisons.
- L-nucleoside reference: CH64037 provides the L-guanosine identity for nucleoside chemistry research.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 135484501
PubChem · CID 135484501
Frequently Asked Questions
How is L-guanosine different from guanosine?
L-Guanosine is the L-enantiomer, or mirror-image form, of natural D-guanosine. They share molecular formula and mass but have opposite chirality; natural guanosine is cataloged separately.
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