L-5-Methyluridine
Oligonucleotide Synthesis, RNA Raw Materials & Modification
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- MF
- C10H14N2O6
- MW
- 258.23
- Purity
- >=98%
L-5-Methyluridine, also called L-ribothymidine, is the L-enantiomer, or mirror-image form, of natural D-5-methyluridine. CH64040 is identified by CAS 642082-80-2, molecular formula C10H14N2O6, molecular weight 258.23, and PubChem CID 1715220.
The cited Spiegelmer literature discusses L-configured oligonucleotides as mirror-image systems with high biostability in nuclease-related studies. CH64040 provides the L-5-methyluridine identity for related L-RNA, Spiegelmer aptamer, and nucleoside stereochemistry research.
Synonyms
L-5-Methyluridine; L-ribothymidine; β-L-5-methyluridine
Identity and specifications
| Catalog No. | CH64040 |
| CAS No. | 642082-80-2 |
| Molecular Formula | C10H14N2O6 |
| Molecular Weight | 258.23 |
| PubChem CID | 1715220 |
| InChIKey | DWRXFEITVBNRMK-AZRUVXNYSA-N |
| Purity | >=98% |
Storage conditions
2-8 C
Technical attributes
- Nucleobase
- 5-Methyluracil
- Sugar
- L-Ribose
- Nucleoside class
- Modified pyrimidine L-ribonucleoside
- Research role
- Mirror-image nucleic-acid building-block reference
- Packaging
- Custom packaging on request
- Physical form
- White to off-white powder
Application context
- Mirror-image / Spiegelmer research: CH64040 is relevant to studies of mirror-image (L-RNA) oligonucleotides and Spiegelmer aptamers.
- Enantiomeric nucleoside studies: L-5-methyluridine provides the 5-methyluridine mirror-image identity for stereochemistry and biostability comparisons.
- L-nucleoside reference: CH64040 provides the L-5-methyluridine identity for nucleoside chemistry research.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 1715220
PubChem · CID 1715220
Frequently Asked Questions
How is L-5-methyluridine different from 5-methyluridine?
L-5-Methyluridine (L-ribothymidine) is the L-enantiomer, or mirror-image form, of natural D-5-methyluridine. They share molecular formula and mass but have opposite chirality; the natural form is cataloged separately.
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