7-Deaza-7-Iodo-2'-deoxyguanosine
Oligonucleotide Synthesis, RNA Raw Materials & Modification
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- MF
- C11H13IN4O4
- MW
- 392.15
- Purity
- >=98%
7-Deaza-7-Iodo-2'-deoxyguanosine is 7-deaza-2'-deoxyguanosine carrying an iodine at the C7 position of the pyrrolo[2,3-d]pyrimidine base. CH64047 is identified by CAS 172163-62-1, molecular formula C11H13IN4O4, molecular weight 392.15, PubChem CID 135405252, and InChIKey TVQBNMOSBBMRCZ-RRKCRQDMSA-N.
In the cited 7-deazapurine literature, the C7-halogen position is discussed as a functionalization point for palladium cross-coupling reactions such as Sonogashira or Suzuki coupling. CH64047 provides the 7-deaza-7-iodo-dG identity for C7-functionalized oligonucleotide research.
Synonyms
7-Deaza-7-iodo-2'-deoxyguanosine; 7-iodo-c7dG
Identity and specifications
| Catalog No. | CH64047 |
| CAS No. | 172163-62-1 |
| Molecular Formula | C11H13IN4O4 |
| Molecular Weight | 392.15 |
| PubChem CID | 135405252 |
| InChIKey | TVQBNMOSBBMRCZ-RRKCRQDMSA-N |
| Purity | >=98% |
Storage conditions
-20 C
Technical attributes
- Nucleobase analog
- 7-Deazaguanine
- Sugar
- 2'-Deoxyribose
- Base modification
- 7-Deaza
- C7 substituent
- Iodo cross-coupling handle
- Packaging
- 250 mg; 500 mg; 1 g; Custom packaging on request
- Physical form
- Solid
- Stability
- >=4 years
Application context
- C7 cross-coupling research: the C7-iodine on the 7-deazapurine base is relevant to Sonogashira/Suzuki-style functionalization studies for C7-modified oligonucleotides.
- Modified-DNA studies: CH64047 combines the N7-removed 7-deazapurine scaffold with a C7 halogen position for base-analog research.
- Base-analog reference: CH64047 provides the 7-deaza-7-iodo-2'-deoxyguanosine identity for nucleoside chemistry research.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 135405252
PubChem · CID 135405252
Frequently Asked Questions
How is this different from 7-deaza-2'-deoxyguanosine?
It is 7-deaza-2'-deoxyguanosine with an added iodine at C7. The plain 7-deaza-dG is listed separately by CHEMOS.
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