5-Iodo-2'-deoxyuridine
Oligonucleotide Synthesis, RNA Raw Materials & Modification
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- MF
- C9H11IN2O5
- MW
- 354.10
- Purity
- 99.6% (HPLC)
5-Iodo-2'-deoxyuridine (IUdR) is 2'-deoxyuridine bearing an iodine at the C5 position of uracil, making it a thymidine analog. CH64060 is identified by CAS 54-42-2, molecular formula C9H11IN2O5, molecular weight 354.10, PubChem CID 5905, and InChIKey XQFRJNBWHJMXHO-RRKCRQDMSA-N.
The cited literature reports IUdR as a thymidine analog incorporated into DNA of S-phase cells. CH64060 is framed as a halogenated-pyrimidine nucleoside for DNA-incorporation and modified-DNA research.
Identity and specifications
| Catalog No. | CH64060 |
| CAS No. | 54-42-2 |
| Molecular Formula | C9H11IN2O5 |
| Molecular Weight | 354.10 |
| PubChem CID | 5905 |
| InChIKey | XQFRJNBWHJMXHO-RRKCRQDMSA-N |
| Purity | 99.6% (HPLC) |
Storage conditions
Room temperature; recommended cool and dark below 15 C
Technical attributes
- Nucleobase
- Uracil
- Sugar
- 2'-Deoxyribose
- Base substituent
- 5-Iodo
- Nucleoside class
- Halogenated pyrimidine deoxyribonucleoside
- Packaging
- 1 g; 5 g; 25 g; Custom packaging on request
- Water content
- 0.4% loss on drying (KF), lot result
- Physical form
- solid; white to almost white powder to crystal
- Stability
- >=4 years
Application context
- S-phase DNA-incorporation research: the cited literature reports 5-iodo-2'-deoxyuridine as a thymidine analog incorporated into newly synthesized DNA in S-phase cells.
- Halogenated-pyrimidine studies: the C5 iodine supports modified-DNA base-analog research contexts.
- Base-analog reference: CH64060 provides the 5-iodo-2'-deoxyuridine identity for nucleoside chemistry research.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 5905
PubChem · CID 5905
Frequently Asked Questions
How does it differ from 2'-deoxyuridine?
It carries an iodine at the C5 position of uracil (a heavy atom), whereas 2'-deoxyuridine is unsubstituted. 2'-deoxyuridine is cataloged separately.
Similar Products
Need Help with Material Selection?
CHEMOS can review product fit, target structure, route questions, analytical expectations, and project-specific supply needs.