5-Iodo-2'-deoxycytidine
Oligonucleotide Synthesis, RNA Raw Materials & Modification
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- MF
- C9H12IN3O4
- MW
- 353.11
- Purity
- 99.8% (HPLC)
5-Iodo-2'-deoxycytidine is 2'-deoxycytidine bearing an iodine at the C5 position of cytosine. CH64061 is identified by CAS 611-53-0, molecular formula C9H12IN3O4, molecular weight 353.11, PubChem CID 65050, and InChIKey WEVJJMPVVFNAHZ-RRKCRQDMSA-N.
The C5 iodine is a heavy atom on the pyrimidine base. CH64061 provides the 5-iodocytosine deoxynucleoside identity for halogenated-pyrimidine, modified-DNA, and nucleoside chemistry research.
Synonyms
5-Iodo-2'-deoxycytidine; 5-iodo-dC
Identity and specifications
| Catalog No. | CH64061 |
| CAS No. | 611-53-0 |
| Molecular Formula | C9H12IN3O4 |
| Molecular Weight | 353.11 |
| PubChem CID | 65050 |
| InChIKey | WEVJJMPVVFNAHZ-RRKCRQDMSA-N |
| Purity | 99.8% (HPLC) |
Storage conditions
-20 C
Technical attributes
- Nucleobase
- Cytosine
- Sugar
- 2'-Deoxyribose
- Base substituent
- 5-Iodo
- Nucleoside class
- Halogenated pyrimidine deoxyribonucleoside
- Grade
- N (Normal)
- Packaging
- 1 g; Custom packaging on request
- Physical form
- solid; white to almost white powder to crystal
- Stability
- >=4 years
Application context
- Halogenated pyrimidine research: the C5 iodine on cytosine supports heavy-atom base-analog work in modified-DNA and nucleoside chemistry research.
- Base-analog reference: CH64061 provides the 5-iodo-2'-deoxycytidine identity for nucleoside chemistry research.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 65050
PubChem · CID 65050
Frequently Asked Questions
How does 5-iodo-2'-deoxycytidine differ from 2'-deoxycytidine?
It carries an iodine at the C5 position of cytosine (a heavy atom), whereas 2'-deoxycytidine is unsubstituted. 2'-deoxycytidine is cataloged separately.
How is it related to 5-iodo-2'-deoxyuridine?
Both are C5-iodinated (heavy-atom) pyrimidine deoxynucleosides; this one has a cytosine base, while 5-iodo-2'-deoxyuridine has a uracil base. Both are cataloged separately.
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