8-Iodoadenosine
Oligonucleotide Synthesis, RNA Raw Materials & Modification
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- MF
- C10H12IN5O4
- MW
- 393.14
- Purity
- 97%
8-Iodoadenosine is adenosine bearing an iodine at the C8 position of adenine. CH64062 is identified by CAS 31281-88-6, molecular formula C10H12IN5O4, molecular weight 393.14, PubChem CID 12803302, and InChIKey CYOIMLAHGVOKIG-UUOKFMHZSA-N.
The cited literature discusses 8-substituted purine nucleosides and nucleotides in relation to syn/anti glycosidic conformation. CH64062 provides the 8-iodoadenosine identity for conformational, base-analog, and C8-functionalization research contexts.
Synonyms
8-Iodoadenosine; 8-I-adenosine
Identity and specifications
| Catalog No. | CH64062 |
| CAS No. | 31281-88-6 |
| Molecular Formula | C10H12IN5O4 |
| Molecular Weight | 393.14 |
| PubChem CID | 12803302 |
| InChIKey | CYOIMLAHGVOKIG-UUOKFMHZSA-N |
| Purity | 97% |
Storage conditions
2-8 C; under dark
Technical attributes
- Nucleobase
- Adenine
- Sugar
- D-Ribose
- Base substituent
- 8-Iodo
- Research role
- C8-functionalization handle
- Packaging
- Custom packaging on request
- Physical form
- solid
Application context
- syn-Conformation research: the cited literature discusses 8-substituted purines as systems with defined syn/anti glycosidic conformational behavior.
- C8-functionalization studies: the C8 iodine marks a chemically addressable position on the adenine base for nucleoside research.
- Base-analog reference: CH64062 provides the 8-iodoadenosine identity for nucleoside chemistry research.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 12803302
PubChem · CID 12803302
Frequently Asked Questions
How does it differ from adenosine?
It carries an iodine at the C8 position of adenine, whereas adenosine is unsubstituted. Adenosine is cataloged separately.
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