8-Iodoguanosine
Oligonucleotide Synthesis, RNA Raw Materials & Modification
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- MF
- C10H12IN5O5
- MW
- 409.14
- Purity
- >=97% (HPLC)
8-Iodoguanosine is guanosine bearing an iodine at the C8 position of guanine. CH64063 is identified by CAS 18438-99-8, molecular formula C10H12IN5O5, molecular weight 409.14, PubChem CID 136226295, and InChIKey PBEHMRJESXYIKX-UMMCILCDSA-N.
The cited literature discusses 8-substituted purine nucleosides and nucleotides in relation to syn/anti glycosidic conformation. CH64063 provides the 8-iodoguanosine identity for conformational, base-analog, and C8-functionalization research contexts.
Synonyms
8-Iodoguanosine; 8-I-guanosine
Identity and specifications
| Catalog No. | CH64063 |
| CAS No. | 18438-99-8 |
| Molecular Formula | C10H12IN5O5 |
| Molecular Weight | 409.14 |
| PubChem CID | 136226295 |
| InChIKey | PBEHMRJESXYIKX-UMMCILCDSA-N |
| Purity | >=97% (HPLC) |
Technical attributes
- Nucleobase
- Guanine
- Sugar
- D-Ribose
- Base substituent
- 8-Iodo
- Research role
- C8-functionalization handle
- Packaging
- 1 g; Custom packaging on request
- Physical form
- Solid
Application context
- syn-Conformation research: the cited literature discusses 8-substituted purines as systems with defined syn/anti glycosidic conformational behavior.
- C8-functionalization studies: the C8 iodine marks a chemically addressable position on the guanine base for nucleoside research.
- Base-analog reference: CH64063 provides the 8-iodoguanosine identity for nucleoside chemistry research.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 136226295
PubChem · CID 136226295
Frequently Asked Questions
How does it differ from guanosine?
It carries an iodine at the C8 position of guanine, whereas guanosine is unsubstituted. Guanosine is cataloged separately.
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