N6-Methyl-2'-deoxyadenosine
Oligonucleotide Synthesis, RNA Raw Materials & Modification
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- MF
- C11H15N5O3
- MW
- 265.27
- Purity
- >=99.0% (HPLC)
N6-Methyl-2'-deoxyadenosine is 2'-deoxyadenosine methylated at the adenine N6 position, corresponding to the nucleoside form of DNA N6-methyladenine (6mA). CH64079 is identified by CAS 2002-35-9, molecular formula C11H15N5O3, molecular weight 265.27, PubChem CID 168948, and InChIKey DYSDOYRQWBDGQQ-XLPZGREQSA-N.
The cited literature discusses DNA N6-methyladenine (6mA) as an adenine-methylation epigenetic modification. Unlike acyl-protected building blocks, the N6-methyl group is a permanent base modification, not a removable protecting group.
Synonyms
N6-Methyl-2'-deoxyadenosine; N6-Me-dA; 6mA nucleoside; N6-methyl-dA
Identity and specifications
| Catalog No. | CH64079 |
| CAS No. | 2002-35-9 |
| Molecular Formula | C11H15N5O3 |
| Molecular Weight | 265.27 |
| PubChem CID | 168948 |
| InChIKey | DYSDOYRQWBDGQQ-XLPZGREQSA-N |
| Purity | >=99.0% (HPLC) |
Storage conditions
-20 C
Technical attributes
- Nucleobase
- Adenine
- Sugar
- 2'-Deoxyribose
- Base modification
- N6-Methyl (6mA)
- Research role
- DNA epigenetic-mark nucleoside reference
- Packaging
- 25 mg; 100 mg; Custom packaging on request
- Water content
- <=5.0% KF
- Physical form
- white powder
- Stability
- >=4 years
Application context
- 6mA epigenetic-mark research: CH64079 is the nucleoside form of DNA N6-methyladenine (6mA), an adenine-methylation epigenetic modification discussed in the cited literature.
- Base-modified nucleoside reference: CH64079 provides the N6-methyl-2'-deoxyadenosine identity for nucleoside chemistry research.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 168948
PubChem · CID 168948
Frequently Asked Questions
Is the N6-methyl group a protecting group?
No. Unlike the N6-acyl (benzoyl/acetyl) building blocks, the N6-methyl here is a permanent base modification — the nucleoside form of the DNA epigenetic mark N6-methyladenine (6mA) — not a group that is removed during deprotection.
What is 6mA?
6mA (N6-methyladenine) is an adenine-methylation epigenetic modification in DNA. CH64079 is the corresponding N6-methyl-2'-deoxyadenosine nucleoside identity.
Similar Products
Need Help with Material Selection?
CHEMOS can review product fit, target structure, route questions, analytical expectations, and project-specific supply needs.