dATP, 100 mM Solution
Oligonucleotide Synthesis, RNA Raw Materials & Modification
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- MF
- C10H13N5Na3O12P3
- MW
- 557.13
- Purity
- 99.98%
dATP, 100 mM Solution is 2'-deoxyadenosine-5'-triphosphate (dATP) listed as a 100 mM aqueous solution of the trisodium salt. Key identifiers include CAS 54680-12-5, molecular formula C10H13N5Na3O12P3, and molecular weight 557.13 (PubChem CID 71650350).
dATP is one of the four canonical deoxynucleoside triphosphates (dNTPs). DNA polymerases catalyze the template-directed polymerization of dNTP substrates onto the 3'-end of a growing DNA primer strand, so dATP supplies the adenine (A) residue during enzymatic DNA synthesis — for example in PCR, primer extension, DNA sequencing, and nick translation.
Synonyms
2'-deoxyadenosine 5'-triphosphate trisodium salt; dATP·3Na, 100 mM aqueous solution
Identity and specifications
| Catalog No. | CH66001 |
| CAS No. | 54680-12-5 |
| Molecular Formula | C10H13N5Na3O12P3 (trisodium salt) |
| Molecular Weight | 557.13 |
| PubChem CID | 71650350 |
| InChIKey | VEESQMCFNINIMU-PWDLANNDSA-K |
| Concentration | 100 mM aqueous solution |
| Purity | 99.98% |
Storage conditions
-20 C; avoid freeze-thaw cycles and frequent temperature changes
Technical attributes
- Nucleotide class
- dNTP
- Nucleobase
- Adenine
- 5'-phosphate state
- Triphosphate
- Grade
- PCR Grade
- Packaging
- 100 µL; 1 mL; 5 mL; 10 mL; 50 mL; Custom packaging on request
- Solution concentration
- 100 mM +/- 3
- Physical form
- clear colorless solution
- Stability
- 2 years
Application context
- Adenine dNTP substrate: supplies the adenine (A) residue during enzymatic, template-directed DNA synthesis by DNA polymerases.
- Common reactions: PCR, primer extension, DNA sequencing, nick translation, and other polymerase-based DNA synthesis reactions.
- Solution presentation: listed as a 100 mM aqueous solution of the trisodium salt.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 71650350
PubChem · CID 71650350
Frequently Asked Questions
What is dATP used for?
dATP is the adenine deoxynucleoside triphosphate. DNA polymerases use it as a substrate to add adenine (A) residues during enzymatic, template-directed DNA synthesis — for example in PCR, primer extension, sequencing, and nick translation.
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