dGTP, 100 mM Solution
Oligonucleotide Synthesis, RNA Raw Materials & Modification
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- MF
- C10H13N5Na3O13P3
- MW
- 573.13
- Purity
- 99.98%
dGTP, 100 mM Solution is 2'-deoxyguanosine-5'-triphosphate (dGTP) listed as a 100 mM aqueous solution of the trisodium salt. Key identifiers include CAS 93919-41-6, molecular formula C10H13N5Na3O13P3, and molecular weight 573.13 (PubChem CID 135705223).
dGTP is one of the four canonical deoxynucleoside triphosphates (dNTPs). DNA polymerases catalyze the template-directed polymerization of dNTP substrates onto the 3'-end of a growing DNA primer strand, so dGTP supplies the guanine (G) residue during enzymatic DNA synthesis — for example in PCR, primer extension, DNA sequencing, and nick translation.
Synonyms
2'-deoxyguanosine 5'-triphosphate trisodium salt; dGTP·3Na, 100 mM aqueous solution
Identity and specifications
| Catalog No. | CH66003 |
| CAS No. | 93919-41-6 |
| Molecular Formula | C10H13N5Na3O13P3 (neutral trisodium salt representation) |
| Molecular Weight | 573.13 |
| PubChem CID | 135705223 |
| Concentration | 100 mM aqueous solution |
| InChIKey | IWGGLKOTEOCWQP-BIHLCPNHSA-K |
| Purity | 99.98% |
Storage conditions
-20 C
Technical attributes
- Nucleotide class
- dNTP
- Nucleobase
- Guanine
- 5'-phosphate state
- Triphosphate
- Grade
- PCR Grade
- Packaging
- 100 µL; 400 µL; 500 µL; 1 mL; 5 mL; 10 mL; 25 mL; 50 mL; 250 mL; 400 mL; Custom packaging on request
- Solution concentration
- 100 mM
- Physical form
- colorless transparent solution
- Stability
- 2 years
Application context
- Guanine dNTP substrate: supplies the guanine (G) residue during enzymatic, template-directed DNA synthesis by DNA polymerases.
- Common reactions: PCR, primer extension, DNA sequencing, nick translation, and other polymerase-based DNA synthesis reactions.
- Solution presentation: listed as a 100 mM aqueous solution of the trisodium salt.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 135705223
PubChem · CID 135705223
Frequently Asked Questions
What is dGTP used for?
dGTP is the guanine deoxynucleoside triphosphate. DNA polymerases use it as a substrate to add guanine (G) residues during enzymatic, template-directed DNA synthesis — for example in PCR, primer extension, sequencing, and nick translation.
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