dITP, 100 mM Solution
Oligonucleotide Synthesis, RNA Raw Materials & Modification
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- MF
- C10H12N4Na3O13P3
- MW
- 558.11
- Purity
- >=99% (HPLC)
dITP, 100 mM Solution is the trisodium salt of 2'-deoxyinosine-5'-triphosphate, listed as a 100 mM solution. Key identifiers are CAS 95648-77-4, molecular formula C10H12N4Na3O13P3, molecular weight 558.11, and PubChem CID 135705217.
dITP is a deoxynucleoside triphosphate carrying a hypoxanthine base. It is used as a substrate in enzymatic DNA synthesis. Published PCR work reports that incorporation of dITP or 7-deaza-dGTP improves sequencing of the resulting product.
Synonyms
2'-deoxyinosine 5'-triphosphate trisodium salt; dITP trisodium salt; dITP, 100 mM solution
Identity and specifications
| Catalog No. | CH66006 |
| CAS No. | 95648-77-4 |
| Compound | 2'-deoxyinosine-5'-triphosphate trisodium salt |
| Molecular Formula | C10H12N4Na3O13P3 |
| Molecular Weight | 558.11 |
| PubChem CID | 135705217 |
| Concentration | 100 mM solution |
| InChIKey | FHYSVBOUQFJKCI-PWDLANNDSA-K |
| Purity | >=99% (HPLC) |
Storage conditions
-20 C
Technical attributes
- Nucleotide class
- dNTP
- Nucleobase
- Hypoxanthine
- 5'-phosphate state
- Triphosphate
- Grade
- PCR Grade
- Packaging
- 250 µL; 1 mL; 10 mL; 100 mL; 25 µmol; 10 mmol; Custom packaging on request
- Solution concentration
- 100 mM to 110 mM
- Physical form
- clear aqueous solution
- Stability
- 12 months
Application context
- Deoxyinosine nucleotide substrate: dITP provides a hypoxanthine-base deoxynucleoside triphosphate for enzymatic DNA synthesis.
- PCR-product sequencing research: incorporation of dITP or 7-deaza-dGTP during PCR has been reported to improve sequencing of the product.
- Solution presentation: listed as a 100 mM solution.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 135705217
PubChem · CID 135705217
Frequently Asked Questions
What is dITP used for?
dITP is deoxyinosine triphosphate, a nucleotide substrate for enzymatic DNA synthesis. Published PCR work reports that incorporation of dITP or 7-deaza-dGTP can improve sequencing of the resulting product.
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