2'-O,4'-C-Methylene-adenosine
(1S,3R,4R,7S)-3-(6-aminopurin-9-yl)-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-7-ol
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Chemical Name
- (1S,3R,4R,7S)-3-(6-aminopurin-9-yl)-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-7-ol
- MF
- C11H13N5O4
- MW
- 279.25
- Purity
- 99.98%
2'-O,4'-C-Methylene-adenosine is catalog CH70052, with CAS 206055-70-1, molecular formula C11H13N5O4, molecular weight 279.25, and PubChem CID 44436074. PubChem lists InChIKey GHKDRNDFVCEETA-KYAGDKKUSA-N for this identity.
A modified nucleoside reference for nucleic-acid chemistry catalog search and structure matching.
Identity and specifications
| Catalog No. | CH70052 |
| Product Name | 2'-O,4'-C-Methylene-adenosine |
| CAS No. | 206055-70-1 |
| PubChem CID | 44436074 |
| Molecular Formula | C11H13N5O4 |
| Molecular Weight | 279.25 |
| Exact Mass | 279.09675391 |
| Monoisotopic Mass | 279.09675391 |
| InChIKey | GHKDRNDFVCEETA-KYAGDKKUSA-N |
| Structural Note | modified nucleoside identity |
| Purity | 99.98% |
Storage conditions
4 C for solid; -80 C or -20 C in solvent; protect from light
Technical attributes
- Material class
- LNA nucleoside
- Nucleobase
- Adenine
- Sugar bridge
- 2'-O,4'-C-methylene
- Protection state
- Unprotected
- Packaging
- 5 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g; 5 g; Custom packaging on request
- Physical form
- White to off-white solid
- Stability
- 6 months at -80 C or 1 month at -20 C in solvent
Application context
- 2'-O,4'-C-Methylene-adenosine reference: use this modified nucleoside building block record for nucleic-acid chemistry catalog work.
- Identifier cross-check: compare CAS 206055-70-1, PubChem CID 44436074, formula C11H13N5O4, MW 279.25, and the listed InChIKey for catalog identity matching.
- Inquiry preparation: include catalog number CH70052, the product name, and the identity-matching identifiers when preparing a CHEMOS product inquiry.
Additional material information
Uses
Use these identifiers to match 2'-O,4'-C-Methylene-adenosine against catalog records, PubChem references, and research-use product records.
Characteristics
2'-O,4'-C-Methylene-adenosine is presented as a modified nucleoside identity with CAS 206055-70-1, PubChem CID 44436074, molecular formula C11H13N5O4, molecular weight 279.25, and InChIKey GHKDRNDFVCEETA-KYAGDKKUSA-N.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 44436074
PubChem · CID 44436074
Frequently Asked Questions
What is 2'-O,4'-C-Methylene-adenosine?
2'-O,4'-C-Methylene-adenosine is catalog CH70052. PubChem lists CID 44436074, molecular formula C11H13N5O4, molecular weight 279.25, and the InChIKey shown in the specification table.
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