2'-O,4'-C-Methylene-guanosine
2-amino-9-[(1S,3R,4R,7S)-7-hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-1H-purin-6-one
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Chemical Name
- 2-amino-9-[(1S,3R,4R,7S)-7-hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-1H-purin-6-one
- MF
- C11H13N5O5
- MW
- 295.25
- Purity
- 99.22%
2'-O,4'-C-Methylene-guanosine is catalog CH70053, with CAS 207131-16-6, molecular formula C11H13N5O5, molecular weight 295.25, and PubChem CID 136404736. PubChem lists InChIKey OZVMOEUWPMYRQU-JUQFDLSGSA-N for this identity.
A modified nucleoside reference for nucleic-acid chemistry catalog search and structure matching.
Identity and specifications
| Catalog No. | CH70053 |
| Product Name | 2'-O,4'-C-Methylene-guanosine |
| CAS No. | 207131-16-6 |
| PubChem CID | 136404736 |
| Molecular Formula | C11H13N5O5 |
| Molecular Weight | 295.25 |
| Exact Mass | 295.09166853 |
| Monoisotopic Mass | 295.09166853 |
| InChIKey | OZVMOEUWPMYRQU-JUQFDLSGSA-N |
| Structural Note | modified nucleoside identity |
| Purity | 99.22% |
Storage conditions
2-8 C; keep dark under inert atmosphere
Technical attributes
- Material class
- LNA nucleoside
- Nucleobase
- Guanine
- Sugar bridge
- 2'-O,4'-C-methylene
- Protection state
- Unprotected
- Packaging
- 5 mg; 10 mg; 100 mg; 250 mg; 500 mg; 1 g; Custom packaging on request
- Physical form
- Solid
- Stability
- 6 months at -80 C or 1 month at -20 C in solvent
Application context
- 2'-O,4'-C-Methylene-guanosine reference: use this modified nucleoside building block record for nucleic-acid chemistry catalog work.
- Identifier cross-check: compare CAS 207131-16-6, PubChem CID 136404736, formula C11H13N5O5, MW 295.25, and the listed InChIKey for catalog identity matching.
- Inquiry preparation: include catalog number CH70053, the product name, and the identity-matching identifiers when preparing a CHEMOS product inquiry.
Additional material information
Uses
Use these identifiers to match 2'-O,4'-C-Methylene-guanosine against catalog records, PubChem references, and research-use product records.
Characteristics
2'-O,4'-C-Methylene-guanosine is presented as a modified nucleoside identity with CAS 207131-16-6, PubChem CID 136404736, molecular formula C11H13N5O5, molecular weight 295.25, and InChIKey OZVMOEUWPMYRQU-JUQFDLSGSA-N.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 136404736
PubChem · CID 136404736
Frequently Asked Questions
What is 2'-O,4'-C-Methylene-guanosine?
2'-O,4'-C-Methylene-guanosine is catalog CH70053. PubChem lists CID 136404736, molecular formula C11H13N5O5, molecular weight 295.25, and the InChIKey shown in the specification table.
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