2'-O-Hexadecyl-2-aminoadenosine
(2R,3R,4R,5R)-5-(2,6-diaminopurin-9-yl)-4-hexadecoxy-2-(hydroxymethyl)oxolan-3-ol
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Chemical Name
- (2R,3R,4R,5R)-5-(2,6-diaminopurin-9-yl)-4-hexadecoxy-2-(hydroxymethyl)oxolan-3-ol
- MF
- C26H46N6O4
- MW
- 506.7
- Purity
- 98%
2'-O-Hexadecyl-2-aminoadenosine is a long-chain 2'-O-alkyl modified nucleoside: a 2,6-diaminopurine nucleoside with a 2'-O-hexadecyl/hexadecoxy sugar substituent. Key identifiers include CAS 2382942-28-9, molecular formula C26H46N6O4, molecular weight 506.7, and PubChem CID 168450040.
This entry is best used as a structure and identifier reference for 2'-O-hexadecyl modified nucleoside cataloging. It should not be presented as a protected CE phosphoramidite monomer or as evidence for delivery, uptake, solubility, or performance claims.
Synonyms
2'-O-hexadecyl-2-aminoadenosine; 2'-O-C16-2-aminoadenosine
Identity and specifications
| Catalog No. | CH70055 |
| CAS No. | 2382942-28-9 |
| Molecular Formula | C26H46N6O4 |
| Molecular Weight | 506.7 |
| Exact Mass | 506.35805397 |
| PubChem CID | 168450040 |
| InChIKey | LWEQWTRVPUIMLN-PTGPVQHPSA-N |
| Structural Note | 2,6-diaminopurine nucleoside with a 2'-O-hexadecyl sugar substituent |
| Purity | 98% |
Storage conditions
-20 C for powder; -80 C in solvent
Technical attributes
- Material class
- 2'-O-alkyl nucleoside
- Nucleobase
- 2,6-Diaminopurine
- Sugar modification
- 2'-O-hexadecyl
- Protection state
- Unprotected
- Packaging
- 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; Custom packaging on request
- Stability
- 3 years at -20 C for powder; 1 year at -80 C in solvent
Application context
- Modified-nucleoside reference: a long-chain 2'-O-alkyl 2-aminoadenosine identity for oligonucleotide chemistry cataloging.
- 2'-O-hexadecyl series matching: useful as a CAS, formula, molecular-weight, and PubChem CID reference for 2'-O-hexadecyl nucleoside searches.
- Structure-aware catalog context: distinguishes the unprotected modified nucleoside from protected phosphoramidite monomers.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 168450040
PubChem · CID 168450040
Frequently Asked Questions
What is 2'-O-Hexadecyl-2-aminoadenosine?
It is a long-chain 2'-O-alkyl modified nucleoside: a 2,6-diaminopurine nucleoside with a 2'-O-hexadecyl sugar substituent. PubChem confirms CAS 2382942-28-9 as CID 168450040.
Is CH70055 a phosphoramidite monomer?
No. CH70055 is documented as the modified nucleoside 2'-O-Hexadecyl-2-aminoadenosine. A protected CE phosphoramidite would require separate structural evidence and identifiers.
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