2'-O-Hexadecyl-uridine
1-[(2R,3R,4R,5R)-3-hexadecoxy-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Chemical Name
- 1-[(2R,3R,4R,5R)-3-hexadecoxy-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
- MF
- C25H44N2O6
- MW
- 468.6
- Purity
- >=97%
2'-O-Hexadecyl-uridine is a long-chain 2'-O-alkyl modified uridine with a 2'-O-hexadecyl/hexadecoxy sugar substituent. Key identifiers include CAS 2382942-69-8, molecular formula C25H44N2O6, molecular weight 468.6, and PubChem CID 122480558.
This entry is best used as a structure and identifier reference for 2'-O-hexadecyl modified uridine cataloging. It should not be presented as a protected CE phosphoramidite monomer or as evidence for delivery, uptake, solubility, or performance claims.
Synonyms
2'-O-hexadecyluridine; 2'-O-C16 uridine
Identity and specifications
| Catalog No. | CH70060 |
| CAS No. | 2382942-69-8 |
| Molecular Formula | C25H44N2O6 |
| Molecular Weight | 468.6 |
| Exact Mass | 468.31993713 |
| PubChem CID | 122480558 |
| InChIKey | SLIDHFCKSCWDEF-MSNJVRRCSA-N |
| Structural Note | Uridine analogue with a 2'-O-hexadecyl sugar substituent |
| Purity | >=97% |
Storage conditions
2-8 C
Technical attributes
- Material class
- 2'-O-alkyl nucleoside
- Nucleobase
- Uracil
- Sugar modification
- 2'-O-hexadecyl
- Protection state
- Unprotected
- Packaging
- Custom packaging on request
- Physical form
- White or off-white solid
Application context
- Modified-uridine reference: a long-chain 2'-O-alkyl uridine identity for oligonucleotide chemistry cataloging.
- 2'-O-hexadecyl series matching: useful as a CAS, formula, molecular-weight, and PubChem CID reference for 2'-O-hexadecyl uridine searches.
- Structure-aware catalog context: distinguishes the unprotected modified nucleoside from protected phosphoramidite monomers.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 122480558
PubChem · CID 122480558
Frequently Asked Questions
What is 2'-O-Hexadecyl-uridine?
It is a long-chain 2'-O-alkyl modified uridine with a 2'-O-hexadecyl sugar substituent. PubChem confirms CAS 2382942-69-8 as CID 122480558.
Is CH70060 a phosphoramidite monomer?
No. CH70060 is documented as the modified nucleoside 2'-O-Hexadecyl-uridine. A protected CE phosphoramidite would require separate structural evidence and identifiers.
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