2'-O-TBDMS-5-methyluridine
1-[(2R,3R,4R,5R)-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Chemical Name
- 1-[(2R,3R,4R,5R)-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
- MF
- C16H28N2O6Si
- MW
- 372.49
- Purity
- >98.00%
2'-O-TBDMS-5-methyluridine is catalog CH70226, with CAS 922508-26-7, molecular formula C16H28N2O6Si, molecular weight 372.49, and PubChem CID 16098978. PubChem lists InChIKey PWAAFDSCYLYFMA-HKUMRIAESA-N for this identity.
A modified nucleoside reference for nucleic-acid chemistry catalog search and structure matching.
Identity and specifications
| Catalog No. | CH70226 |
| Product Name | 2'-O-TBDMS-5-methyluridine |
| CAS No. | 922508-26-7 |
| PubChem CID | 16098978 |
| Molecular Formula | C16H28N2O6Si |
| Molecular Weight | 372.49 |
| Exact Mass | 372.17166315 |
| Monoisotopic Mass | 372.17166315 |
| InChIKey | PWAAFDSCYLYFMA-HKUMRIAESA-N |
| Structural Note | modified nucleoside identity |
| Purity | >98.00% |
Storage conditions
2-8 C
Technical attributes
- Material class
- 2'-O-TBDMS ribonucleoside
- Nucleobase
- 5-Methyluracil
- 2'-O protection
- TBDMS
- Synthesis stage
- Protected nucleoside intermediate
- Packaging
- 1 g; Custom packaging on request
- Physical form
- solid
Application context
- 2'-O-TBDMS-5-methyluridine reference: use this modified nucleoside building block record for nucleic-acid chemistry catalog work.
- Identifier cross-check: compare CAS 922508-26-7, PubChem CID 16098978, formula C16H28N2O6Si, MW 372.49, and the listed InChIKey for catalog identity matching.
- Inquiry preparation: include catalog number CH70226, the product name, and the identity-matching identifiers when preparing a CHEMOS product inquiry.
Additional material information
Uses
Use these identifiers to match 2'-O-TBDMS-5-methyluridine against catalog records, PubChem references, and research-use product records.
Characteristics
2'-O-TBDMS-5-methyluridine is presented as a modified nucleoside identity with CAS 922508-26-7, PubChem CID 16098978, molecular formula C16H28N2O6Si, molecular weight 372.49, and InChIKey PWAAFDSCYLYFMA-HKUMRIAESA-N.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 16098978
PubChem · CID 16098978
Frequently Asked Questions
What is 2'-O-TBDMS-5-methyluridine?
2'-O-TBDMS-5-methyluridine is catalog CH70226. PubChem lists CID 16098978, molecular formula C16H28N2O6Si, molecular weight 372.49, and the InChIKey shown in the specification table.
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