2'-O-TBDMS-pU-CE-Phosphoramidite
3-[[(2R,3R,4S,5S)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxy-5-(2,4-dioxo-1H-pyrimidin-5-yl)oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Chemical Name
- 3-[[(2R,3R,4S,5S)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxy-5-(2,4-dioxo-1H-pyrimidin-5-yl)oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
- MF
- C45H61N4O9PSi
- MW
- 861.0
- Purity
- >=95%
2'-O-TBDMS-pU-CE-Phosphoramidite is catalog CH70235, with CAS 163496-23-9, molecular formula C45H61N4O9PSi, molecular weight 861.0, and PubChem CID 125459309. PubChem lists InChIKey JPJHNALDAAZFFN-LMNGBUJGSA-N for this identity.
A protected CE phosphoramidite reference for identifying this modified nucleoside monomer in oligonucleotide synthesis catalogs.
Identity and specifications
| Catalog No. | CH70235 |
| Product Name | 2'-O-TBDMS-pU-CE-Phosphoramidite |
| CAS No. | 163496-23-9 |
| PubChem CID | 125459309 |
| Molecular Formula | C45H61N4O9PSi |
| Molecular Weight | 861.0 |
| Exact Mass | 860.39454307 |
| Monoisotopic Mass | 860.39454307 |
| InChIKey | JPJHNALDAAZFFN-LMNGBUJGSA-N |
| Structural Note | protected nucleoside CE phosphoramidite identity |
| Purity | >=95% |
Storage conditions
-20 C
Technical attributes
- Monomer class
- Pseudouridine CE phosphoramidite
- Nucleoside identity
- Pseudouridine
- 2'-O protection
- TBDMS
- Coupling group
- 3'-O-CE phosphoramidite
- Grade
- for Nucleic Acid Synthesis
- Packaging
- 250 mg; 1 g; Custom packaging on request
- Water content
- <=0.1%
- Physical form
- white, off-white to light yellow powder
Application context
- 2'-O-TBDMS-pU-CE-Phosphoramidite reference: use this CE phosphoramidite monomer record for oligonucleotide synthesis monomer catalog work.
- Identifier cross-check: compare CAS 163496-23-9, PubChem CID 125459309, formula C45H61N4O9PSi, MW 861.0, and the listed InChIKey for catalog identity matching.
- Inquiry preparation: include catalog number CH70235, the product name, and the identity-matching identifiers when preparing a CHEMOS product inquiry.
Additional material information
Uses
Use these identifiers to match 2'-O-TBDMS-pU-CE-Phosphoramidite against catalog records, PubChem references, and research-use product records.
Characteristics
2'-O-TBDMS-pU-CE-Phosphoramidite is presented as a protected nucleoside CE phosphoramidite identity with CAS 163496-23-9, PubChem CID 125459309, molecular formula C45H61N4O9PSi, molecular weight 861.0, and InChIKey JPJHNALDAAZFFN-LMNGBUJGSA-N.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 125459309
PubChem · CID 125459309
Frequently Asked Questions
What is 2'-O-TBDMS-pU-CE-Phosphoramidite?
2'-O-TBDMS-pU-CE-Phosphoramidite is catalog CH70235. PubChem lists CID 125459309, molecular formula C45H61N4O9PSi, molecular weight 861.0, and the InChIKey shown in the specification table.
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