2'-O-TBDMS-uridine
1-[(2R,3R,4R,5R)-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Chemical Name
- 1-[(2R,3R,4R,5R)-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
- MF
- C15H26N2O6Si
- MW
- 358.46
- Purity
- >=97% (HPLC)
2'-O-TBDMS-uridine is catalog CH70237, with CAS 54925-71-2, molecular formula C15H26N2O6Si, molecular weight 358.46, and PubChem CID 11233661. PubChem lists InChIKey AYQZFVZTNUOLCQ-OJAKKHQRSA-N for this identity.
A modified nucleoside reference for nucleic-acid chemistry catalog search and structure matching.
Identity and specifications
| Catalog No. | CH70237 |
| Product Name | 2'-O-TBDMS-uridine |
| CAS No. | 54925-71-2 |
| PubChem CID | 11233661 |
| Molecular Formula | C15H26N2O6Si |
| Molecular Weight | 358.46 |
| Exact Mass | 358.15601309 |
| Monoisotopic Mass | 358.15601309 |
| InChIKey | AYQZFVZTNUOLCQ-OJAKKHQRSA-N |
| Structural Note | modified nucleoside identity |
| Purity | >=97% (HPLC) |
Storage conditions
room temperature
Technical attributes
- Material class
- 2'-O-TBDMS ribonucleoside
- Nucleobase
- Uracil
- 2'-O protection
- TBDMS
- Synthesis stage
- Protected nucleoside intermediate
- Packaging
- 1 g; 2 g; 5 g; 10 g; 25 g; Custom packaging on request
- Physical form
- white to off-white crystalline powder
Application context
- 2'-O-TBDMS-uridine reference: use this modified nucleoside building block record for nucleic-acid chemistry catalog work.
- Identifier cross-check: compare CAS 54925-71-2, PubChem CID 11233661, formula C15H26N2O6Si, MW 358.46, and the listed InChIKey for catalog identity matching.
- Inquiry preparation: include catalog number CH70237, the product name, and the identity-matching identifiers when preparing a CHEMOS product inquiry.
Additional material information
Uses
Use these identifiers to match 2'-O-TBDMS-uridine against catalog records, PubChem references, and research-use product records.
Characteristics
2'-O-TBDMS-uridine is presented as a modified nucleoside identity with CAS 54925-71-2, PubChem CID 11233661, molecular formula C15H26N2O6Si, molecular weight 358.46, and InChIKey AYQZFVZTNUOLCQ-OJAKKHQRSA-N.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 11233661
PubChem · CID 11233661
Frequently Asked Questions
What is 2'-O-TBDMS-uridine?
2'-O-TBDMS-uridine is catalog CH70237. PubChem lists CID 11233661, molecular formula C15H26N2O6Si, molecular weight 358.46, and the InChIKey shown in the specification table.
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