3',5'-Di-O-TBDMS-2'-O-methyluridine
1-[(2R,3R,4R,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-[[tert-butyl(dimethyl)silyl]oxymethyl]-3-methoxyoxolan-2-yl]pyrimidine-2,4-dione
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Chemical Name
- 1-[(2R,3R,4R,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-[[tert-butyl(dimethyl)silyl]oxymethyl]-3-methoxyoxolan-2-yl]pyrimidine-2,4-dione
- MF
- C22H42N2O6Si2
- MW
- 486.7
- Purity
- 95%
3',5'-Di-O-TBDMS-2'-O-methyluridine is catalog CH70266, with CAS 367511-37-3, molecular formula C22H42N2O6Si2, molecular weight 486.7, and PubChem CID 69539383. PubChem lists InChIKey NZGTXWSGCBMHTB-NXWXRZEISA-N for this identity.
A modified nucleoside reference for nucleic-acid chemistry catalog search and structure matching.
Identity and specifications
| Catalog No. | CH70266 |
| Product Name | 3',5'-Di-O-TBDMS-2'-O-methyluridine |
| CAS No. | 367511-37-3 |
| PubChem CID | 69539383 |
| Molecular Formula | C22H42N2O6Si2 |
| Molecular Weight | 486.7 |
| Exact Mass | 486.25814013 |
| Monoisotopic Mass | 486.25814013 |
| InChIKey | NZGTXWSGCBMHTB-NXWXRZEISA-N |
| Structural Note | modified nucleoside identity |
| Purity | 95% |
Storage conditions
2-8 C; argon charged
Technical attributes
- Material class
- Protected 2'-O-methyl nucleoside
- Nucleobase
- Uracil
- Sugar modification
- 2'-O-methyl
- Silyl protection
- 3',5'-Di-O-TBDMS
- Packaging
- 250 mg; 1 g; 5 g; Custom packaging on request
Application context
- 3',5'-Di-O-TBDMS-2'-O-methyluridine reference: use this modified nucleoside building block record for nucleic-acid chemistry catalog work.
- Identifier cross-check: compare CAS 367511-37-3, PubChem CID 69539383, formula C22H42N2O6Si2, MW 486.7, and the listed InChIKey for catalog identity matching.
- Inquiry preparation: include catalog number CH70266, the product name, and the identity-matching identifiers when preparing a CHEMOS product inquiry.
Additional material information
Uses
Use these identifiers to match 3',5'-Di-O-TBDMS-2'-O-methyluridine against catalog records, PubChem references, and research-use product records.
Characteristics
3',5'-Di-O-TBDMS-2'-O-methyluridine is presented as a modified nucleoside identity with CAS 367511-37-3, PubChem CID 69539383, molecular formula C22H42N2O6Si2, molecular weight 486.7, and InChIKey NZGTXWSGCBMHTB-NXWXRZEISA-N.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 69539383
PubChem · CID 69539383
Frequently Asked Questions
What is 3',5'-Di-O-TBDMS-2'-O-methyluridine?
3',5'-Di-O-TBDMS-2'-O-methyluridine is catalog CH70266. PubChem lists CID 69539383, molecular formula C22H42N2O6Si2, molecular weight 486.7, and the InChIKey shown in the specification table.
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