3'-O-TBDMS-2'-O-methyl-N6-benzoyladenosine
N-[9-[(2R,3R,4R,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]purin-6-yl]benzamide
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Chemical Name
- N-[9-[(2R,3R,4R,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]purin-6-yl]benzamide
- MF
- C24H33N5O5Si
- MW
- 499.6
- Purity
- >=98% (HPLC)
3'-O-TBDMS-2'-O-methyl-N6-benzoyladenosine is catalog CH70280, with CAS 454424-09-0, molecular formula C24H33N5O5Si, molecular weight 499.6, and PubChem CID 169448809. PubChem lists InChIKey ROHHXNDVYNHGRQ-DYVMYPEFSA-N for this identity.
A modified nucleoside reference for nucleic-acid chemistry catalog search and structure matching.
Identity and specifications
| Catalog No. | CH70280 |
| Product Name | 3'-O-TBDMS-2'-O-methyl-N6-benzoyladenosine |
| CAS No. | 454424-09-0 |
| PubChem CID | 169448809 |
| Molecular Formula | C24H33N5O5Si |
| Molecular Weight | 499.6 |
| Exact Mass | 499.22509570 |
| Monoisotopic Mass | 499.22509570 |
| InChIKey | ROHHXNDVYNHGRQ-DYVMYPEFSA-N |
| Structural Note | modified nucleoside identity |
| Purity | >=98% (HPLC) |
Storage conditions
2-8 C
Technical attributes
- Material class
- Protected 2'-O-methyl nucleoside
- Nucleobase
- Adenine
- Sugar modification
- 2'-O-methyl
- Protection pattern
- 3'-O-TBDMS; N6-benzoyl
- Packaging
- Custom packaging on request
Application context
- 3'-O-TBDMS-2'-O-methyl-N6-benzoyladenosine reference: use this modified nucleoside building block record for nucleic-acid chemistry catalog work.
- Identifier cross-check: compare CAS 454424-09-0, PubChem CID 169448809, formula C24H33N5O5Si, MW 499.6, and the listed InChIKey for catalog identity matching.
- Inquiry preparation: include catalog number CH70280, the product name, and the identity-matching identifiers when preparing a CHEMOS product inquiry.
Additional material information
Uses
Use these identifiers to match 3'-O-TBDMS-2'-O-methyl-N6-benzoyladenosine against catalog records, PubChem references, and research-use product records.
Characteristics
3'-O-TBDMS-2'-O-methyl-N6-benzoyladenosine is presented as a modified nucleoside identity with CAS 454424-09-0, PubChem CID 169448809, molecular formula C24H33N5O5Si, molecular weight 499.6, and InChIKey ROHHXNDVYNHGRQ-DYVMYPEFSA-N.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 169448809
PubChem · CID 169448809
Frequently Asked Questions
What is 3'-O-TBDMS-2'-O-methyl-N6-benzoyladenosine?
3'-O-TBDMS-2'-O-methyl-N6-benzoyladenosine is catalog CH70280. PubChem lists CID 169448809, molecular formula C24H33N5O5Si, molecular weight 499.6, and the InChIKey shown in the specification table.
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