3'-O-TBDMS-2'-O-methyluridine
1-[(2R,3R,4R,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]pyrimidine-2,4-dione
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Chemical Name
- 1-[(2R,3R,4R,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]pyrimidine-2,4-dione
- MF
- C16H28N2O6Si
- MW
- 372.49
- Purity
- 98%
3'-O-TBDMS-2'-O-methyluridine is catalog CH70281, with CAS 171268-84-1, molecular formula C16H28N2O6Si, molecular weight 372.49, and PubChem CID 66869720. PubChem lists InChIKey VWMFRWSCFRRALN-FMKGYKFTSA-N for this identity.
A modified nucleoside reference for nucleic-acid chemistry catalog search and structure matching.
Identity and specifications
| Catalog No. | CH70281 |
| Product Name | 3'-O-TBDMS-2'-O-methyluridine |
| CAS No. | 171268-84-1 |
| PubChem CID | 66869720 |
| Molecular Formula | C16H28N2O6Si |
| Molecular Weight | 372.49 |
| Exact Mass | 372.17166315 |
| Monoisotopic Mass | 372.17166315 |
| InChIKey | VWMFRWSCFRRALN-FMKGYKFTSA-N |
| Structural Note | modified nucleoside identity |
| Purity | 98% |
Technical attributes
- Material class
- Protected 2'-O-methyl nucleoside
- Nucleobase
- Uracil
- Sugar modification
- 2'-O-methyl
- Silyl protection
- 3'-O-TBDMS
- Packaging
- 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g; 250 g; Custom packaging on request
Application context
- 3'-O-TBDMS-2'-O-methyluridine reference: use this modified nucleoside building block record for nucleic-acid chemistry catalog work.
- Identifier cross-check: compare CAS 171268-84-1, PubChem CID 66869720, formula C16H28N2O6Si, MW 372.49, and the listed InChIKey for catalog identity matching.
- Inquiry preparation: include catalog number CH70281, the product name, and the identity-matching identifiers when preparing a CHEMOS product inquiry.
Additional material information
Uses
Use these identifiers to match 3'-O-TBDMS-2'-O-methyluridine against catalog records, PubChem references, and research-use product records.
Characteristics
3'-O-TBDMS-2'-O-methyluridine is presented as a modified nucleoside identity with CAS 171268-84-1, PubChem CID 66869720, molecular formula C16H28N2O6Si, molecular weight 372.49, and InChIKey VWMFRWSCFRRALN-FMKGYKFTSA-N.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 66869720
PubChem · CID 66869720
Frequently Asked Questions
What is 3'-O-TBDMS-2'-O-methyluridine?
3'-O-TBDMS-2'-O-methyluridine is catalog CH70281. PubChem lists CID 66869720, molecular formula C16H28N2O6Si, molecular weight 372.49, and the InChIKey shown in the specification table.
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