5'-(E)-VP-2'-OMe-3'-O-TBDMS-A(Bz)
[[(E)-2-[(2R,3R,4R,5R)-5-(6-benzamidopurin-9-yl)-3-[tert-butyl(dimethyl)silyl]oxy-4-methoxyoxolan-2-yl]ethenyl]-(2,2-dimethylpropanoyloxymethoxy)phosphoryl]oxymethyl 2,2-dimethylpropanoate
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Chemical Name
- [[(E)-2-[(2R,3R,4R,5R)-5-(6-benzamidopurin-9-yl)-3-[tert-butyl(dimethyl)silyl]oxy-4-methoxyoxolan-2-yl]ethenyl]-(2,2-dimethylpropanoyloxymethoxy)phosphoryl]oxymethyl 2,2-dimethylpropanoate
- MF
- C37H54N5O11PSi
- MW
- 803.9
- Purity
- >=98%
5'-(E)-VP-2'-OMe-3'-O-TBDMS-A(Bz) is catalog CH70286, with CAS 2419895-58-0, molecular formula C37H54N5O11PSi, molecular weight 803.9, and PubChem CID 171390956. PubChem lists InChIKey ACMRRKRFEWHRPJ-ZOBIAEOYSA-N for this identity.
A modified nucleoside reference for nucleic-acid chemistry catalog search and structure matching.
Identity and specifications
| Catalog No. | CH70286 |
| Product Name | 5'-(E)-VP-2'-OMe-3'-O-TBDMS-A(Bz) |
| CAS No. | 2419895-58-0 |
| PubChem CID | 171390956 |
| Molecular Formula | C37H54N5O11PSi |
| Molecular Weight | 803.9 |
| Exact Mass | 803.33267109 |
| Monoisotopic Mass | 803.33267109 |
| InChIKey | ACMRRKRFEWHRPJ-ZOBIAEOYSA-N |
| Structural Note | specialty building-block identity |
| Purity | >=98% |
Technical attributes
- Material class
- Protected 5'-(E)-vinylphosphonate nucleoside
- Nucleobase
- Adenine
- Sugar modification
- 2'-O-methyl
- Protection pattern
- 3'-O-TBDMS; N6-benzoyl
- Packaging
- Custom packaging on request
Application context
- 5'-(E)-VP-2'-OMe-3'-O-TBDMS-A(Bz) reference: use this modified nucleoside building block record for nucleic-acid chemistry catalog work.
- Identifier cross-check: compare CAS 2419895-58-0, PubChem CID 171390956, formula C37H54N5O11PSi, MW 803.9, and the listed InChIKey for catalog identity matching.
- Inquiry preparation: include catalog number CH70286, the product name, and the identity-matching identifiers when preparing a CHEMOS product inquiry.
Additional material information
Uses
Use these identifiers to match 5'-(E)-VP-2'-OMe-3'-O-TBDMS-A(Bz) against catalog records, PubChem references, and research-use product records.
Characteristics
5'-(E)-VP-2'-OMe-3'-O-TBDMS-A(Bz) is presented as a specialty building-block identity with CAS 2419895-58-0, PubChem CID 171390956, molecular formula C37H54N5O11PSi, molecular weight 803.9, and InChIKey ACMRRKRFEWHRPJ-ZOBIAEOYSA-N.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 171390956
PubChem · CID 171390956
Frequently Asked Questions
What is 5'-(E)-VP-2'-OMe-3'-O-TBDMS-A(Bz)?
5'-(E)-VP-2'-OMe-3'-O-TBDMS-A(Bz) is catalog CH70286. PubChem lists CID 171390956, molecular formula C37H54N5O11PSi, molecular weight 803.9, and the InChIKey shown in the specification table.
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