5'-O-DMT-2'-O-propargyl-N2-isobutyrylguanosine
N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-prop-2-ynoxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Chemical Name
- N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-prop-2-ynoxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
- MF
- C38H39N5O8
- MW
- 693.7
- Purity
- 99.98%
5'-O-DMT-2'-O-propargyl-N2-isobutyrylguanosine is 5'-DMT 2'-O-propargyl N2-isobutyryl guanosine. Key identifiers include CAS 171486-53-6, molecular formula C38H39N5O8, molecular weight 693.7, PubChem CID 136628033, and InChIKey ZTBYTNLGRCUAEU-BEGXHNNXSA-N.
The PubChem structure supports a protected modified nucleoside intermediate: it has a 5'-O-DMT-protected scaffold and no CE phosphoramidite group. Keep the page focused on identity and research-use catalog context.
Identity and specifications
| Catalog No. | CH70326 |
| CAS No. | 171486-53-6 |
| Molecular Formula | C38H39N5O8 |
| Molecular Weight | 693.7 |
| PubChem CID | 136628033 |
| InChIKey | ZTBYTNLGRCUAEU-BEGXHNNXSA-N |
| Purity | 99.98% |
Storage conditions
Powder: -20 C; in solvent: -80 C
Technical attributes
- Material class
- Protected 2'-O-propargyl nucleoside
- Nucleobase
- Guanine
- Sugar modification
- 2'-O-propargyl
- Protection pattern
- 5'-O-DMT; N2-isobutyryl
- Packaging
- 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; Custom packaging on request
- Stability
- Powder: 3 years; in solvent: 1 year
Application context
- 5'-O-DMT-2'-O-propargyl-N2-isobutyrylguanosine reference: use this protected modified nucleoside building block record for oligonucleotide and nucleoside-analog catalog work.
- Identifier cross-check: compare CAS 171486-53-6, PubChem CID 136628033, formula C38H39N5O8, MW 693.7, and the listed InChIKey for catalog identity matching.
- Inquiry preparation: include catalog number CH70326, the product name, and the identity-matching identifiers when preparing a CHEMOS product inquiry.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 136628033
PubChem · CID 136628033
Frequently Asked Questions
What is 5'-O-DMT-2'-O-propargyl-N2-isobutyrylguanosine?
5'-O-DMT-2'-O-propargyl-N2-isobutyrylguanosine is catalog CH70326, CAS 171486-53-6. PubChem CID 136628033 confirms formula C38H39N5O8, molecular weight 693.7, and InChIKey ZTBYTNLGRCUAEU-BEGXHNNXSA-N.
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