5'-O-DMT-2'-O-propargyluridine
1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-prop-2-ynoxyoxolan-2-yl]pyrimidine-2,4-dione
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Chemical Name
- 1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-prop-2-ynoxyoxolan-2-yl]pyrimidine-2,4-dione
- MF
- C33H32N2O8
- MW
- 584.6
- Purity
- >=98%
5'-O-DMT-2'-O-propargyluridine is 5'-DMT 2'-O-propargyl uridine. Key identifiers include CAS 171486-54-7, molecular formula C33H32N2O8, molecular weight 584.6, PubChem CID 22885209, and InChIKey VFYMBSPPKISNAZ-PMFUCWTESA-N.
The PubChem structure supports a protected modified nucleoside intermediate: it has a 5'-O-DMT-protected scaffold and no CE phosphoramidite group. Keep the page focused on identity and research-use catalog context. PubChem also returns non-stereospecific CID 18926862 for the same CAS. The page selects stereochemically defined CID 22885209.
Identity and specifications
| Catalog No. | CH70329 |
| CAS No. | 171486-54-7 |
| Molecular Formula | C33H32N2O8 |
| Molecular Weight | 584.6 |
| PubChem CID | 22885209 |
| InChIKey | VFYMBSPPKISNAZ-PMFUCWTESA-N |
| Purity | >=98% |
Storage conditions
Sealed at 0-5 C
Technical attributes
- Material class
- Protected 2'-O-propargyl nucleoside
- Nucleobase
- Uracil
- Sugar modification
- 2'-O-propargyl
- Protection pattern
- 5'-O-DMT; base unprotected
- Packaging
- Custom packaging on request
- Physical form
- White or off-white solid
Application context
- 5'-O-DMT-2'-O-propargyluridine reference: use this protected modified nucleoside building block record for oligonucleotide and nucleoside-analog catalog work.
- Identifier cross-check: compare CAS 171486-54-7, PubChem CID 22885209, formula C33H32N2O8, MW 584.6, and the listed InChIKey for catalog identity matching.
- Inquiry preparation: include catalog number CH70329, the product name, and the identity-matching identifiers when preparing a CHEMOS product inquiry.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 22885209
PubChem · CID 22885209
Frequently Asked Questions
What is 5'-O-DMT-2'-O-propargyluridine?
5'-O-DMT-2'-O-propargyluridine is catalog CH70329, CAS 171486-54-7. PubChem CID 22885209 confirms formula C33H32N2O8, molecular weight 584.6, and InChIKey VFYMBSPPKISNAZ-PMFUCWTESA-N.
Similar Products
Need Help with Material Selection?
CHEMOS can review product fit, target structure, route questions, analytical expectations, and project-specific supply needs.