O(6)-NPE-N(2)-iBu protected Morpholino G subunit
N-[9-[(2R,6S)-6-[[chloro(dimethylamino)phosphoryl]oxymethyl]-4-tritylmorpholin-2-yl]-6-[2-(4-nitrophenyl)ethoxy]purin-2-yl]-2-methylpropanamide
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Chemical Name
- N-[9-[(2R,6S)-6-[[chloro(dimethylamino)phosphoryl]oxymethyl]-4-tritylmorpholin-2-yl]-6-[2-(4-nitrophenyl)ethoxy]purin-2-yl]-2-methylpropanamide
- MF
- C43H46ClN8O7P
- MW
- 853.3
- Purity
- >=98.0% (HPLC)
O(6)-NPE-N(2)-iBu protected Morpholino G subunit is O6-NPE N2-iBu protected morpholino guanine subunit. Key identifiers include CAS 2708274-72-8, molecular formula C43H46ClN8O7P, molecular weight 853.3, PubChem CID 162343835, and InChIKey WAHZVPMCAUKPIH-BZIXDFOGSA-N.
The PubChem structure supports a protected morpholino subunit identity rather than a standard nucleoside CE phosphoramidite. Use it as a structure-confirmed catalog identity for morpholino building-block research; do not add PMO performance or biological-use claims.
Identity and specifications
| Catalog No. | CH70428 |
| CAS No. | 2708274-72-8 |
| Molecular Formula | C43H46ClN8O7P |
| Molecular Weight | 853.3 |
| PubChem CID | 162343835 |
| InChIKey | WAHZVPMCAUKPIH-BZIXDFOGSA-N |
| Purity | >=98.0% (HPLC) |
Storage conditions
-20 C
Technical attributes
- Subunit class
- Protected morpholino subunit
- Nucleobase
- Guanine
- O6 protection
- NPE
- N2 protection
- Isobutyryl
- Packaging
- Custom packaging on request
- Water content
- <=0.5%
- Physical form
- White to faint yellow powder, free from visible foreign matter
Application context
- O(6)-NPE-N(2)-iBu protected Morpholino G subunit reference: use this protected morpholino subunit record for morpholino building-block catalog work.
- Identifier cross-check: compare CAS 2708274-72-8, PubChem CID 162343835, formula C43H46ClN8O7P, MW 853.3, and the listed InChIKey for catalog identity matching.
- Inquiry preparation: include catalog number CH70428, the product name, and the identity-matching identifiers when preparing a CHEMOS product inquiry.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 162343835
PubChem · CID 162343835
Frequently Asked Questions
What is O(6)-NPE-N(2)-iBu protected Morpholino G subunit?
O(6)-NPE-N(2)-iBu protected Morpholino G subunit is catalog CH70428, CAS 2708274-72-8. PubChem CID 162343835 confirms formula C43H46ClN8O7P, molecular weight 853.3, and InChIKey WAHZVPMCAUKPIH-BZIXDFOGSA-N.
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