U-(S)-GNA Phosphoramidite
3-[[(2S)-1-[bis(4-methoxyphenyl)-phenylmethoxy]-3-(2,4-dioxopyrimidin-1-yl)propan-2-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Chemical Name
- 3-[[(2S)-1-[bis(4-methoxyphenyl)-phenylmethoxy]-3-(2,4-dioxopyrimidin-1-yl)propan-2-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
- MF
- C37H45N4O7P
- MW
- 688.7
- Purity
- 98%
U-(S)-GNA Phosphoramidite is catalog CH70436. PubChem resolves CAS 494784-15-5 to CID 101397881, with molecular formula C37H45N4O7P, molecular weight 688.7, exact mass 688.30258678, and InChIKey KZZGGKJIAMPACS-AQXIKWHWSA-N.
This entry describes an (S)-GNA-U phosphoramidite building block with a uracil base, DMT-protected hydroxyl, and 2-cyanoethyl N,N-diisopropyl phosphoramidite group for modified oligonucleotide synthesis research.
Synonyms
(S)-GNA-U-phosphoramidite; U-(S)-GNA Phosphoramidite (source name)
Identity and specifications
| Catalog No. | CH70436 |
| Product Name | U-(S)-GNA Phosphoramidite |
| CAS No. | 494784-15-5 |
| Molecular Formula | C37H45N4O7P |
| Molecular Weight | 688.7 |
| Exact Mass | 688.30258678 |
| PubChem CID | 101397881 |
| InChIKey | KZZGGKJIAMPACS-AQXIKWHWSA-N |
| Synonyms | (S)-GNA-U-phosphoramidite; GNA-U phosphoramidite; CAS 494784-15-5 |
| Purity | 98% |
Storage conditions
-20 C
Technical attributes
- Monomer class
- GNA CE phosphoramidite
- Nucleobase
- Uracil
- GNA configuration
- (S)
- O-protection
- DMT
- Grade
- N (Normal)
- Packaging
- 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; Custom packaging on request
- Physical form
- White, off-white to light yellow powder, free from visible foreign matter
Application context
- GNA-U phosphoramidite: CAS 494784-15-5 and PubChem CID 101397881 support an (S)-GNA-U phosphoramidite identity for modified oligonucleotide synthesis research.
- GNA series cataloging: use this entry when organizing glycol nucleic acid phosphoramidite building blocks alongside related GNA base variants.
- Structure matching: formula C37H45N4O7P and InChIKey KZZGGKJIAMPACS-AQXIKWHWSA-N help align this catalog entry with current product specifications.
Additional material information
Uses
Use this catalog entry for research-oriented identity matching, GNA phosphoramidite catalog searches, and modified oligonucleotide synthesis planning.
Characteristics
U-(S)-GNA Phosphoramidite is represented here as a specialty glycol nucleic acid phosphoramidite. Use the CAS number, PubChem CID, formula, exact mass, and InChIKey when aligning this catalog entry with product specifications.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 101397881
PubChem · CID 101397881
Frequently Asked Questions
What is U-(S)-GNA Phosphoramidite?
U-(S)-GNA Phosphoramidite is catalog CH70436. PubChem resolves CAS 494784-15-5 to CID 101397881, with formula C37H45N4O7P and molecular weight 688.7.
Which GNA base variant does this entry represent?
PubChem synonym data supports the (S)-GNA-U phosphoramidite identity, corresponding to the uracil GNA phosphoramidite entry.
Similar Products
Need Help with Material Selection?
CHEMOS can review product fit, target structure, route questions, analytical expectations, and project-specific supply needs.