5-Me-CTP
[[(2R,3S,4R,5R)-5-(4-amino-5-methyl-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Chemical Name
- [[(2R,3S,4R,5R)-5-(4-amino-5-methyl-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
- MF
- C10H18N3O14P3
- MW
- 497.18
- Purity
- >99.00%
5-Me-CTP is catalog CH70447 for a 5-methyl-CTP / 5-methylcytidine-5'-triphosphate identity. PubChem CID 10207015 records CAS 327174-86-7, molecular formula C10H18N3O14P3, molecular weight 497.18, exact mass 497.00016325, and InChIKey YIJVOACVHQZMKI-JXOAFFINSA-N.
5-Me-CTP is relevant to research workflows involving modified ribonucleoside triphosphates, base-modified nucleoside triphosphate synthesis, and in vitro transcription with modified nucleotides. Salt form and concentration should follow the product specification.
Synonyms
5-methyl-CTP; 5-Me-CTP; 5mCTP; 5-methylcytidine-5'-triphosphate; Cytidine 5'-(tetrahydrogen triphosphate), 5-Methyl-
Identity and specifications
| Catalog No. | CH70447 |
| Product Name | 5-Me-CTP |
| CAS No. | 327174-86-7 |
| PubChem CID | 10207015 |
| PubChem Title | 5-methyl-CTP |
| Molecular Formula | C10H18N3O14P3 |
| Molecular Weight | 497.18 |
| Exact Mass | 497.00016325 |
| InChIKey | YIJVOACVHQZMKI-JXOAFFINSA-N |
| Synonyms | 5-methyl-CTP; 5-Me-CTP; 5mCTP; 5-methylcytidine-5'-triphosphate |
| Purity | >99.00% |
Storage conditions
-70 C for infrequent use; -20 C for daily or weekly use
Technical attributes
- Nucleotide class
- Modified ribonucleoside triphosphate
- Nucleobase
- 5-Methylcytosine
- Sugar
- Ribose
- 5'-phosphate state
- Triphosphate
- Grade
- M (Molecular Biology); S (Endotoxin)
- Packaging
- 1 mL; 10 mL; 0.1 mL centrifuge tube; 1 mL centrifuge tube; 10 mg/vial; 100 mg/vial; 5 mg/vial; 50 mg/vial; Custom packaging on request
- Solution concentration
- 100 mM
- Physical form
- Clear colorless trisodium salt solution
Application context
- Modified nucleotide research: a 5-methylcytidine triphosphate identity for studies involving base-modified ribonucleoside triphosphates.
- Nucleoside triphosphate synthesis: relevant to research contexts around chemical preparation of base-modified nucleoside-5'-triphosphates.
- In vitro transcription context: applicable as a modified nucleotide reference in research workflows involving in vitro transcription with modified nucleotides.
Additional material information
Uses
Use as a research modified nucleotide reference in workflows evaluating 5-Me-CTP, 5-methylcytidine triphosphate, base-modified nucleoside triphosphates, or in vitro transcription with modified nucleotides. Interpret use conditions through the product specification and assay design.
Characteristics
5-Me-CTP maps to a 5-methylcytidine triphosphate identity. PubChem supports the stereochemical 5-methyl-CTP record for CAS 327174-86-7, while salt, concentration, and solution details should follow the product specification.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 10207015
PubChem · CID 10207015
Frequently Asked Questions
What is 5-Me-CTP?
5-Me-CTP is catalog CH70447 for a 5-methyl-CTP / 5-methylcytidine-5'-triphosphate identity. PubChem CID 10207015 is used for the page identity.
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