2'-OMe-pseudouridine
5-[(2S,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-1H-pyrimidine-2,4-dione
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Chemical Name
- 5-[(2S,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-1H-pyrimidine-2,4-dione
- MF
- C10H14N2O6
- MW
- 258.23
- Purity
- 98%
2'-OMe-pseudouridine is catalog CH70075. PubChem CID 9943091 supports the stereospecific 2'-O-methylpseudouridine identity with molecular formula C10H14N2O6, molecular weight 258.23, exact mass 258.08518617, and InChIKey WGNUTGFETAXDTJ-OOJXKGFFSA-N.
This entry describes a modified pseudouridine nucleoside for identity-reference workflows, O-methyl pseudouridine isomer comparison, and oligonucleotide modification catalog context. It is not described here as a nucleotide triphosphate, phosphoramidite, or direct IVT substrate.
Synonyms
2'-O-methylpseudouridine; 2'-O-Methyl-Pseudouridine; 2'-OMe-pseudouridine (source name); CAS 2140-68-3
Identity and specifications
| Catalog No. | CH70075 |
| Product Name | 2'-OMe-pseudouridine |
| CAS No. | 2140-68-3 |
| Molecular Formula | C10H14N2O6 |
| Molecular Weight | 258.23 |
| Exact Mass | 258.08518617 |
| PubChem CID | 9943091 |
| InChIKey | WGNUTGFETAXDTJ-OOJXKGFFSA-N |
| Synonyms | 2'-O-methylpseudouridine; 2'-O-Methyl-Pseudouridine; CAS 2140-68-3 |
| Purity | 98% |
Storage conditions
<-15 C; cool dry and well-ventilated
Technical attributes
- Material class
- 2'-O-methyl pseudouridine
- Sugar modification
- 2'-O-methyl
- Glycosidic linkage
- C-glycosidic
- Protection state
- Unprotected
- Packaging
- 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 1 g; 5 g; 10 g; 25 g; Custom packaging on request
- Physical form
- Powder
Application context
- Modified nucleoside reference: CAS 2140-68-3 and PubChem CID 9943091 support a 2'-O-methyl pseudouridine identity for modified-nucleoside reference work.
- O-methyl pseudouridine isomer comparison: formula C10H14N2O6, molecular weight 258.23, and InChIKey WGNUTGFETAXDTJ-OOJXKGFFSA-N help distinguish this entry from related O-methyl pseudouridine isomers.
- Catalog navigation: use this entry when organizing pseudouridine derivatives within oligonucleotide synthesis and modification catalogs.
Additional material information
Uses
Use this catalog entry for research-oriented identity matching, modified nucleoside reference work, and pseudouridine-derivative catalog searches.
Characteristics
2'-OMe-pseudouridine is represented here as a free modified nucleoside with a PubChem-supported stereospecific identity. Use the CAS number, PubChem CID, formula, exact mass, and InChIKey when aligning this catalog entry with research-use product records.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 9943091
PubChem · CID 9943091
Frequently Asked Questions
What is 2'-OMe-pseudouridine?
2'-OMe-pseudouridine is catalog CH70075. PubChem CID 9943091 supports the CAS 2140-68-3 identity, with formula C10H14N2O6 and molecular weight 258.23.
Why is PubChem CID 9943091 used here?
PubChem CAS lookup returns related records for CAS 2140-68-3. CID 9943091 is the stereospecific 2'-O-methylpseudouridine identity used for this product entry.
Is this product a nucleotide triphosphate or phosphoramidite?
No. This page describes a free modified nucleoside entry. Nucleotide triphosphate or phosphoramidite wording would require a product-specific derivative.
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