N2-Isobutyryl-2'-FANA-2'-deoxyguanosine
N-[9-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Chemical Name
- N-[9-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
- MF
- C14H18FN5O5
- MW
- 355.32
- Purity
- 99%
N2-Isobutyryl-2'-FANA-2'-deoxyguanosine is N2-isobutyryl 2'-FANA guanosine. Key identifiers include CAS 308356-20-9, molecular formula C14H18FN5O5, molecular weight 355.32, PubChem CID 136395929, and InChIKey SLHADUUWJSVYGQ-NDORMNELSA-N.
The 2'F-ANA scaffold has an arabino 2'-fluoro sugar configuration. This page should present the item as a modified nucleoside or protected nucleoside identity reference, not as a CE phosphoramidite unless separate phosphoramidite evidence is supplied.
Identity and specifications
| Catalog No. | CH70125 |
| CAS No. | 308356-20-9 |
| Molecular Formula | C14H18FN5O5 |
| Molecular Weight | 355.32 |
| PubChem CID | 136395929 |
| InChIKey | SLHADUUWJSVYGQ-NDORMNELSA-N |
| Purity | 99% |
Storage conditions
Powder -20 C or 4 C; in solvent -80 C or -20 C
Technical attributes
- Material class
- Protected 2'F-ANA nucleoside
- Nucleobase
- Guanine
- Sugar configuration
- 2'-Deoxy-2'-fluoro-arabino
- Base protection
- N2-isobutyryl
- Packaging
- 5 mg; 10 mg; 25 mg; 500 mg; 1 g; 5 g; 10 g; 50 g; 100 g; 500 g; 1 kg; 10 kg; 100 kg; Custom packaging on request
- Stability
- Powder 3 years at -20 C or 2 years at 4 C; in solvent 6 months at -80 C or 1 month at -20 C
Application context
- N2-Isobutyryl-2'-FANA-2'-deoxyguanosine reference: use this 2'-fluoro arabino nucleoside building block record for modified oligonucleotide building-block review.
- Identifier cross-check: compare CAS 308356-20-9, PubChem CID 136395929, formula C14H18FN5O5, MW 355.32, and the listed InChIKey for catalog identity matching.
- Inquiry preparation: include catalog number CH70125, the product name, and the identity-matching identifiers when preparing a CHEMOS product inquiry.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 136395929
PubChem · CID 136395929
Frequently Asked Questions
What is N2-Isobutyryl-2'-FANA-2'-deoxyguanosine?
N2-Isobutyryl-2'-FANA-2'-deoxyguanosine is catalog CH70125, CAS 308356-20-9. PubChem CID 136395929 confirms formula C14H18FN5O5, molecular weight 355.32, and InChIKey SLHADUUWJSVYGQ-NDORMNELSA-N.
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