ARCA Ammonium Solution
[(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-9-ium-9-yl)-4-hydroxy-3-methoxyoxolan-2-yl]methyl [[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] phosphate
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Chemical Name
- [(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-9-ium-9-yl)-4-hydroxy-3-methoxyoxolan-2-yl]methyl [[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] phosphate
- MF
- C22H31N10O18P3
- MW
- 816.5
- Purity
- >=98% (HPLC)
ARCA Ammonium Solution is catalog CH70450 for an ARCA Cap Analog / 3'-O-Methyl-m7GpppG identity. PubChem CID 137169098 records CAS 400806-46-4, molecular formula C22H31N10O18P3, molecular weight 816.5, exact mass 816.10306517, and InChIKey AIRSQUYUYJSIIM-XPWFQUROSA-N.
ARCA is relevant to research workflows involving anti-reverse cap analogs, dinucleotide mRNA cap analogs, and mRNA 5' cap structure studies. Counterion, solution form, and concentration should follow the product specification.
Synonyms
ARCA Cap Analog; ARCA (anti-reverse cap analog); 3'-O-Methyl-m7GpppG; m27,3'OGpppG; Guanosine 5'-(tetrahydrogen triphosphate), 7-methyl-3'-O-methyl-, inner salt, P''-->5'-ester with guanosine
Identity and specifications
| Catalog No. | CH70450 |
| Product Name | ARCA Ammonium Solution |
| CAS No. | 400806-46-4 |
| PubChem CID | 137169098 |
| Molecular Formula | C22H31N10O18P3 |
| Molecular Weight | 816.5 |
| Exact Mass | 816.10306517 |
| InChIKey | AIRSQUYUYJSIIM-XPWFQUROSA-N |
| Synonyms | ARCA Cap Analog; ARCA (anti-reverse cap analog); 3'-O-Methyl-m7GpppG; m27,3'OGpppG |
| Purity | >=98% (HPLC) |
Storage conditions
-20 C long term
Technical attributes
- Cap analog class
- Dinucleotide triphosphate
- Cap structure
- 3'-O-Methyl-m7GpppG
- Nucleoside pair
- m7G / G
- Linkage
- 5'-5' triphosphate bridge
- Packaging
- 10 µL; Custom packaging on request
- Solution concentration
- 100 mM
- Physical form
- Clear colorless aqueous solution
- Stability
- 12 months unopened after receipt
Application context
- ARCA cap analog research: an anti-reverse cap analog identity for studies involving mRNA 5' cap analog structures.
- Dinucleotide cap analog studies: applicable as a research reference around synthetic dinucleotide mRNA cap analogs and related assay design.
- Cap-structure context: ARCA / 3'-O-Methyl-m7GpppG appears in research involving capped mRNA and cap-structure analysis.
Additional material information
Uses
Use as a research cap analog reference in workflows evaluating ARCA, anti-reverse cap analogs, dinucleotide mRNA cap analogs, or mRNA 5' cap structures. Interpret use conditions through the product specification and assay design.
Characteristics
ARCA is an anti-reverse dinucleotide cap analog identity. PubChem supports the ARCA Cap Analog / 3'-O-Methyl-m7GpppG identity, while ammonium-solution details should follow the product specification.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 137169098
PubChem · CID 137169098
Frequently Asked Questions
What is ARCA Ammonium Solution?
ARCA Ammonium Solution is catalog CH70450 for an ARCA Cap Analog / 3'-O-Methyl-m7GpppG identity. PubChem CID 137169098 is used for the page identity.
Is the ammonium solution form confirmed by PubChem?
No. PubChem supports the ARCA Cap Analog / 3'-O-Methyl-m7GpppG identity. The ammonium counterion, solution form, and concentration should follow the product specification.
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