N7-Me-GTP
[(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-9-ium-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [hydroxy(phosphonooxy)phosphoryl] phosphate
Product summary
Quick view
- Product family
- Oligonucleotide Synthesis, RNA Raw Materials & Modification
- Chemical Name
- [(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-9-ium-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [hydroxy(phosphonooxy)phosphoryl] phosphate
- MF
- C11H18N5O14P3
- MW
- 537.21
- Purity
- >=99.0% (HPLC)
N7-Me-GTP is catalog CH70472 for a 7-Methyl-GTP / m7GTP identity. PubChem CID 135450598 records CAS 26554-26-7, molecular formula C11H18N5O14P3, molecular weight 537.21, exact mass 537.00631126, and InChIKey DKVRNHPCAOHRSI-KQYNXXCUSA-N.
N7-Me-GTP is relevant to research workflows involving methylated cap analogs, m7GTP cap-bound proteins, and cap-structure analysis. Salt form, counterion, solution form, and concentration should follow the product specification.
Synonyms
7-Methyl-GTP; m7GTP; 7-Methylguanosine 5'-triphosphate; Guanosine 5'-(tetrahydrogen triphosphate), 7-methyl-, inner salt
Identity and specifications
| Catalog No. | CH70472 |
| Product Name | N7-Me-GTP |
| CAS No. | 26554-26-7 |
| PubChem CID | 135450598 |
| PubChem Title | 7-methyl-GTP |
| Molecular Formula | C11H18N5O14P3 |
| Molecular Weight | 537.21 |
| Exact Mass | 537.00631126 |
| InChIKey | DKVRNHPCAOHRSI-KQYNXXCUSA-N |
| Synonyms | 7-Methyl-GTP; m7GTP; 7-Methylguanosine 5'-triphosphate; M7GTP inner salt |
| Purity | >=99.0% (HPLC) |
Storage conditions
-20 C
Technical attributes
- Nucleotide class
- Modified GTP analog
- Nucleobase
- N7-Methylguanine
- Sugar
- Ribose
- 5'-phosphate state
- Triphosphate
- Grade
- S (Endotoxin grade)
- Packaging
- 10 mg; 25 mg; Custom packaging on request
- Solution concentration
- 100 mM
- Physical form
- Clear colorless solution
- Stability
- 12 months after date of delivery
Application context
- m7GTP cap analog research: a 7-Methyl-GTP / m7GTP identity for studies involving methylated mRNA cap analog structures.
- Cap-bound protein studies: applicable as a research reference around m7GTP cap-bound initiation-factor and cap-recognition workflows.
- N7-alkylated cap derivatives: relevant to research contexts involving N7-alkylated cap derivative characterization and cap-binding analysis.
Additional material information
Uses
Use as a research cap analog reference in workflows evaluating N7-Me-GTP, m7GTP, methylated cap analogs, cap-bound proteins, or cap-structure recognition. Interpret use conditions through the product specification and assay design.
Characteristics
N7-Me-GTP maps to a methylated guanosine triphosphate cap analog identity. PubChem supports 7-Methyl-GTP / m7GTP records for CAS 26554-26-7, while salt, counterion, and solution details should follow the product specification.
Related technical resources
Oligonucleotide Modification
Sugar, base, backbone, terminal, and conjugation modifications for ASO, siRNA, guide RNA, aptamer, and research or labeling oligo projects.
Oligonucleotide Synthesis
Support for modified monomers, supports, sulfurizing reagents, cap analogs, and related oligo synthesis inputs.
Public references
- Sustainability Challenges and Opportunities in Oligonucleotide Manufacturing
Journal of Organic Chemistry, 2021
Product-family technical context
- Solid-phase supports for oligonucleotide synthesis
Current Protocols in Nucleic Acid Chemistry, 2013
Product-family technical context
- Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
Tetrahedron Letters, 1981
Product-family technical context
- Synthesis of deoxyoligonucleotides on a polymer support
Journal of the American Chemical Society, 1981
Product-family technical context
- PubChem Compound 135450598
PubChem · CID 135450598
Frequently Asked Questions
What is N7-Me-GTP?
N7-Me-GTP is catalog CH70472 for a 7-Methyl-GTP / m7GTP identity. PubChem CID 135450598 is used for the page identity.
Is the sodium salt form confirmed for this page identity?
No. The page identity uses CAS 26554-26-7 for 7-Methyl-GTP / m7GTP. Sodium salt, counterion, solution form, and concentration should follow the product specification.
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