1-Oleoyl-sn-glycero-3-phosphocholine
化学名称
[(2R)-2-hydroxy-3-[(Z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
1-Oleoyl-sn-glycero-3-phosphocholine•LNP
Structure: 
产品编号
CH51035
CAS
19420-56-5
分子式
C26H52NO7P
分子量
521.67
规格标准
| Catalog No. | CH51035 |
| CAS No. | 19420-56-5 |
| Molecular Formula | C26H52NO7P |
| Molecular Weight | 521.67 |
品类工艺支持
CHEMOS supports custom synthesis and process development for LNP lipid components, with work planned according to target structure, requested scale, and analytical requirements. Ionizable lipid route development : route scouting, impurity review, stereochemistry control, and purification planning. Helper lipid and PEG-lipid preparation : support for phospholipids, sterol-related components, PEG-lipids, and related analogs. Analytical support : HPLC, NMR, MS, Karl Fischer water content, elemental analysis, and residual-solvent testing can be discussed by project. Scale-up support : transfer from laboratory preparation to larger pilot or production batches after route and quality review. Project documentation : batch-specific COA and technical information are provided according to the confirmed specification.
概况
1-Oleoyl-sn-glycero-3-phosphocholine (also known as [(2R)-2-hydroxy-3-[(Z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate) (CAS 19420-56-5, MF C26H52NO7P, MW 521.67) is a helper-lipid phospholipid component of relevance to liposome and LNP research. Programs working with this lipid focus on chain-length specificity, oxidation control for unsaturated tails, and analytical separation of related species. Custom synthesis, process scale-up and supply planning are available through CHEMOS R&D and manufacturing facilities.
应用
- 1-Oleoyl-sn-glycero-3-phosphocholine (CAS 19420-56-5) route review and custom analog preparation
- Pulmonary surfactant and biophysical research applications
- Custom synthesis of acyl-chain or head-group variants
- Process-development support for scalable phospholipid preparation