DOTA-Bombesin (1-14)

DOTA-Bombesin (1-14)

DOTA-Bombesin (1-14)DOTA
Structure: DOTA-Bombesin (1-14) structure, CAS 593287-40-2, MW 2042.28
产品编号
CH54012
CAS
593287-40-2
分子式
C90H136N28O25S
分子量
2042.28
规格标准
Catalog No.CH54012
CAS No.593287-40-2
Molecular FormulaC90H136N28O25S
Molecular Weight2042.28

品类工艺支持

CHEMOS supports DOTA chelator and radiopharmaceutical building-block chemistry, including protected, activated, PEG-spaced, and conjugation-ready intermediates. DOTA and DOTA-GA derivatives : protected chelators, activated esters, maleimide derivatives, and linker-spaced variants. Custom chelator-linker synthesis : route design for chelator-linker-targeting moiety intermediates. Metal-sensitive process control : purification and analytical planning for low-metal-background requirements. Analytical support : HPLC, NMR, MS, and ICP-MS can be discussed according to project needs. Scale-up support : process optimization and batch-size planning after technical review.

概况

DOTA-Bombesin (1-14) (CAS 593287-40-2, MF C90H136N28O25S, MW 2042.28) is a DOTA-family macrocyclic chelator building block used in radiopharmaceutical and metal-conjugate research. Programs working with this compound typically focus on selective functionalisation, radiometal compatibility (e.g., ⁹⁰Y, ¹⁷⁷Lu, ⁶⁴Cu), and conjugate stability. CHEMOS process-development team and large production base can support route refinement, scale-up and custom synthesis on request.

应用

  • DOTA-Bombesin (1-14) (CAS 593287-40-2) preparation, route refinement, and analytical-control planning
  • Antibody and peptide radiolabeling research
  • DOTA-conjugate analog synthesis (e.g., DOTATATE-family research)
  • Custom synthesis of mono-functionalised DOTA derivatives

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