NH-CH2-CH2-DOTAM
NH-CH2-CH2-DOTAM•DOTA
Structure: 
产品编号
CH54015
CAS
2685840-60-0
分子量
443.55
规格标准
| Catalog No. | CH54015 |
| CAS No. | 2685840-60-0 |
| Molecular Weight | 443.55 |
品类工艺支持
CHEMOS supports DOTA chelator and radiopharmaceutical building-block chemistry, including protected, activated, PEG-spaced, and conjugation-ready intermediates. DOTA and DOTA-GA derivatives : protected chelators, activated esters, maleimide derivatives, and linker-spaced variants. Custom chelator-linker synthesis : route design for chelator-linker-targeting moiety intermediates. Metal-sensitive process control : purification and analytical planning for low-metal-background requirements. Analytical support : HPLC, NMR, MS, and ICP-MS can be discussed according to project needs. Scale-up support : process optimization and batch-size planning after technical review.
概况
NH-CH2-CH2-DOTAM (CAS 2685840-60-0, MW 443.55) is part of the DOTA chelator family used in targeted radioligand and imaging-conjugate research. Practical chemistry topics include mono-functionalisation of the macrocycle, protection-group strategy, and conjugation chemistry with peptides or antibodies. Custom synthesis, process scale-up and supply planning are available through CHEMOS R&D and manufacturing facilities.
应用
- NH-CH2-CH2-DOTAM (CAS 2685840-60-0) preparation, route refinement, and analytical-control planning
- Custom synthesis of mono-functionalised DOTA derivatives
- Process-development support for scalable chelator preparation
- Trace-metal control studies for radiopharmaceutical conjugates