BCN-DOTA-GA
化学名称
5-[2-[[(1S,8R)-9-bicyclo[6.1.0]non-4-ynyl]methoxycarbonylamino]ethylamino]-5-oxo-2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetrazacyclododec-1-yl]pentanoic acid
BCN-DOTA-GA•DOTA
Structure: 
产品编号
CH54018
CAS
2416980-98-6
分子式
C32H50N6O11
分子量
694.77
规格标准
| Catalog No. | CH54018 |
| CAS No. | 2416980-98-6 |
| Molecular Formula | C32H50N6O11 |
| Molecular Weight | 694.77 |
品类工艺支持
CHEMOS supports DOTA chelator and radiopharmaceutical building-block chemistry, including protected, activated, PEG-spaced, and conjugation-ready intermediates. DOTA and DOTA-GA derivatives : protected chelators, activated esters, maleimide derivatives, and linker-spaced variants. Custom chelator-linker synthesis : route design for chelator-linker-targeting moiety intermediates. Metal-sensitive process control : purification and analytical planning for low-metal-background requirements. Analytical support : HPLC, NMR, MS, and ICP-MS can be discussed according to project needs. Scale-up support : process optimization and batch-size planning after technical review.
概况
BCN-DOTA-GA (also known as 5-[2-[[(1S,8R)-9-bicyclo[6.1.0]non-4-ynyl]methoxycarbonylamino]ethylamino]-5-oxo-2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetrazacyclododec-1-yl]pentanoic acid) (CAS 2416980-98-6, MF C32H50N6O11, MW 694.77) belongs to the DOTA-family chelator class for targeted radiopharmaceutical research. Programs typically examine residual metal control, kinetic inertness of the metal complex, and the available coupling handle. CHEMOS process-development team and large production base can support route refinement, scale-up and custom synthesis on request.
应用
- BCN-DOTA-GA (2416980-98-6) supply and analog preparation for research programs
- Process-development support for scalable chelator preparation
- Trace-metal control studies for radiopharmaceutical conjugates
- Targeted radioligand therapy (TRT) building block — ⁹⁰Y / ¹⁷⁷Lu / ²²⁵Ac conjugates