ADC Linkers & Conjugation Reagents

Mc-Val-Cit-PABC-PNP

Mc-Val-Cit-PABC-PNP

Produkt-Nr.CH53018CAS-Nr.159857-81-5

Mc-Val-Cit-PABC-PNP

Produktübersicht

Kurzüberblick

Produktfamilie: ADC Linkers & Conjugation Reagents
Chemischer Name: Mc-Val-Cit-PABC-PNP
MF: C35H43N7O11
MW: 737.76

Mc-Val-Cit-PABC-PNP is the product name used for CH53018.

CAS 159857-81-5, molecular formula C35H43N7O11, molecular weight about 737.8, and PubChem CID 57587849 match this compound record.

Val-Cit-PABC-PNP is also listed as a synonym for this record.

Identität und Spezifikationen

Catalog No.	CH53018
CAS No.	159857-81-5
Chemical Name	Mc-Val-Cit-PABC-PNP
Synonym	Val-Cit-PABC-PNP
Molecular Formula	C35H43N7O11
Molecular Weight	737.76
PubChem CID	57587849

Zugehörige technische Ressourcen

ADC Linker-Payload-Chemie

Spaltbare oder stabile Linker, hydrophile Spacer, selektive Handles und Payload-Linker-Intermediate.

Spaltbare vs nicht-spaltbare ADC-Linker

Vergleich nach Freisetzungsprodukt, Trigger, Zirkulationsstabilität, Zellverarbeitung, Payload, Konjugation und analytischer Evidenz.

Öffentliche Quellen

N-(6-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl)-L-valyl-N5-(aminocarbonyl)-N-(4-((((4-nitrophenoxy)carbonyl)oxy)methyl)phenyl)-L-ornithinamide | PubChem CID 57587849
Development of Solid-Phase Site-Specific Conjugation and Its Application toward Generation of Dual Labeled Antibody and Fab Drug Conjugates
Bioconjugate Chemistry, 2016
Product-family technical context
Effect of Linker-Drug Properties and Conjugation Site on the Physical Stability of ADCs
Journal of Pharmaceutical Sciences, 2020
Product-family technical context
Antibody-Maytansinoid Conjugates Are Activated in Targeted Cancer Cells by Lysosomal Degradation and Linker-Dependent Intracellular Processing
Cancer Research, 2006
Product-family technical context
The Effect of Different Linkers on Target Cell Catabolism and Pharmacokinetics/Pharmacodynamics of Trastuzumab Maytansinoid Conjugates
Molecular Cancer Therapeutics, 2012
Product-family technical context

Häufig gestellte Fragen

What is Mc-Val-Cit-PABC-PNP?

Mc-Val-Cit-PABC-PNP is the product name used for CH53018.

Ähnliche Produkte

Fmoc-8-amino-3,6-dioxaoctanoic acid structure, CAS 166108-71-0, MW 385.41

Fmoc-8-amino-3,6-dioxaoctanoic acid

CAS-Nr.: 166108-71-0
MF: C21H23NO6
MW: 385.41

Maleimide structure, CAS 541-59-3, MW 97.07

Maleimide

CAS-Nr.: 541-59-3
MF: C4H3NO2
MW: 97.07

Boc-C16-COOH structure, CAS 843666-40-0, MW 370.6

Boc-C16-COOH

CAS-Nr.: 843666-40-0
MF: C22H42O4
MW: 370.6

Boc-Hyp-OH structure, CAS 13726-69-7, MW 231.25

Boc-Hyp-OH

CAS-Nr.: 13726-69-7
MF: C10H17NO5
MW: 231.25

Benötigen Sie Hilfe bei der Materialauswahl?

CHEMOS kann Produktfit, Zielstruktur, Routenfragen, analytische Erwartungen und projektspezifische Lieferbedarfe prüfen.

Projektunterstützung ansehen